SCHEMBL13023988

SCHEMBL13023988

Cc1cc(C)c(N2c3cnccc3Oc3ncccc32)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.38
MAPT P10636 5/20 0.37
POLB P06746 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.33
CYP2A6 P11509 1/20 0.31
TSHR P16473 1/20 0.31
CDK8 P49336 2/20 0.31
TP53 P04637 2/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
ALDH1A1 P00352 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13024017 0.89 LMNA (0.38) LMNAMAPTPOLBSMN1; SMN2TP53
SCHEMBL13023992 0.86 CYP17A1 (0.32)
SCHEMBL13023970 0.85 LMNA (0.39) LMNAMAPTPOLBALDH1A1
SCHEMBL13023975 0.85 RAPGEF4 (0.34) MAPTSMN1; SMN2TP53NPC1RAB9A
SCHEMBL13023980 0.84 MAPT (0.36) LMNAMAPTSMN1; SMN2TP53NPC1
SCHEMBL13024018 0.84 LMNA (0.34) LMNAMAPTPOLB
SCHEMBL13023994 0.84 MAPT (0.31) MAPTPOLB
SCHEMBL13023972 0.82 KMT2A (0.32) LMNAMAPTPOLBSMN1; SMN2CYP2A6
SCHEMBL13024008 0.82
SCHEMBL13023977 0.81 LMNA (0.41) LMNAMAPTPOLBSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 LMNA 1808/4885MAPT 2367/4885POLB 2141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.