SCHEMBL13026464

SCHEMBL13026464

C=Cc1c(/C=C\C)ccc2nccn12

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CDK8 P49336 2/20 0.33
ROCK1 Q13464 2/20 0.33
FLT1 P17948 1/20 0.33
CDK9 P50750 1/20 0.33
LIMK1 P53667 1/20 0.33
CLK4 Q9HAZ1 1/20 0.33
CHEK1 O14757 1/20 0.33
MAP4K4 O95819 1/20 0.33
CSF1R P07333 1/20 0.33
PRKACA P17612 1/20 0.33
KDR P35968 1/20 0.33
MAP2K1 Q02750 1/20 0.33
ACVR1 Q04771 1/20 0.33
MAP4K2 Q12851 1/20 0.33
DYRK1A Q13627 1/20 0.33
AURKB Q96GD4 1/20 0.33
DYRK1B Q9Y463 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12952624 0.89 CDK8 (0.32) CDK8ROCK1FLT1CDK9LIMK1
SCHEMBL19510469 0.75 CDK8 (0.38) CDK8ROCK1FLT1CDK9LIMK1
SCHEMBL18184622 0.68
SCHEMBL22729976 0.67
SCHEMBL14463968 0.65
SCHEMBL5575387 0.65 CDK8 (0.38) CDK8ROCK1FLT1CDK9LIMK1
SCHEMBL18535906 0.65 CA12 (0.32)
SCHEMBL20924432 0.64 GRIN2D (0.31)
SCHEMBL14463965 0.62 NOTUM (0.33)
SCHEMBL19035432 0.61 NPC1 (0.43) FLT1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7854999-B2 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-12-21 US disclosed
US-20080100207-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080100207-A1 Organoelectroluminescent compound and organoelectroluminescent device employing the same PPOX, EML4, DDT CDK8 324/4885ROCK1 1218/4885FLT1 2258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.