⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13030132 | 0.84 | — | — | |
| SCHEMBL13100020 | 0.83 | HCAR3 (0.38) | — | |
| SCHEMBL13029782 | 0.80 | — | — | |
| SCHEMBL2067804 | 0.79 | LPL (0.45) | — | |
| SCHEMBL7876938 | 0.77 | BCL6 (0.32) | — | |
| SCHEMBL10328069 | 0.77 | — | — | |
| SCHEMBL9887683 | 0.77 | — | — | |
| SCHEMBL12229249 | 0.75 | KDM4E (0.32) | — | |
| SCHEMBL13100015 | 0.72 | FFAR1 (0.43) | — | |
| SCHEMBL13100018 | 0.72 | HCAR3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311714-A1 | 1H-IMIDAZO[4,5-c]QUINOLINONE COMPOUNDS | NOVARTIS AG (CH) | 2010-12-09 | — | — | US | disclosed |