Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13982630 | 0.79 | HTT (0.47) | HTTCHKAMAPTTERTBCHE | |
| SCHEMBL15865970 | 0.79 | HTT (0.47) | HTTCHKAMAPTTERTBCHE | |
| SCHEMBL21290572 | 0.79 | HTT (0.61) | HTTCHKAMAPTBCHEACHE | |
| SCHEMBL12533280 | 0.74 | HTT (0.77) | HTTCHKAMAPTBCHEACHE | |
| SCHEMBL18234751 | 0.74 | HTT (0.70) | HTTCHKAMAPTBCHEACHE | |
| Iodide SCHEMBL1932275 | 0.72 | HTT (0.74) | HTTMAPTBCHEACHEKDM4E | |
| SCHEMBL12533274 | 0.72 | HTT (0.82) | HTTCHKAMAPTBCHEACHE | |
| SCHEMBL13990105 | 0.72 | HTT (0.54) | HTTCHKABCHEACHEKDM4E | |
| SCHEMBL2863713 | 0.72 | HTT (0.67) | HTTCHKAMAPTBCHEACHE | |
| SCHEMBL4403595 | 0.72 | HTT (0.82) | HTTCHKAMAPTBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100279340-A1 | Imaging agents for protein misfolding | NYU (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279340-A1 | Imaging agents for protein misfolding | APBA1, APP, SPG11 | HTT 6/4885CHKA 2868/4885MAPT 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.