1,4-Dichlorobenzene

1,4-Dichlorobenzene

SCHEMBL1303192

Clc1ccc(Cl)cc1.O=S(=O)([O-])[O-].[K+].[K+]

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of 1,4-Dichlorobenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.63
CYP3A4 P08684 1/20 0.63
MAPK1 P28482 1/20 0.63
CA1 P00915 7/20 0.57
CA2 P00918 7/20 0.57
CA9 Q16790 4/20 0.57
CA12 O43570 3/20 0.57
CA3 P07451 3/20 0.57
CA4 P22748 3/20 0.57
CA6 P23280 3/20 0.57
CA5A P35218 3/20 0.57
CA7 P43166 3/20 0.57
CA13 Q8N1Q1 3/20 0.57
CA14 Q9ULX7 3/20 0.57
CA5B Q9Y2D0 3/20 0.57
LMNA P02545 1/20 0.53
CYP2A6 P11509 1/20 0.53
MMP2 P08253 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Dichlorobenzene SCHEMBL17801647 0.93 ALDH1A1 (0.63) ALDH1A1CYP3A4MAPK1CA1CA2
Potassium Ion SCHEMBL6568401 0.85 ALDH1A1 (0.62) ALDH1A1CYP3A4MAPK1CA1CA2
Chlorobenzene SCHEMBL28154717 0.85 TSHR (0.61) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL6913638 0.81 ALDH1A1 (0.65) ALDH1A1CYP3A4MAPK1CA1CA2
Potassium Ion SCHEMBL9353228 0.81 ALDH1A1 (0.56) ALDH1A1CYP3A4MAPK1CA1CA2
4-Chloroaniline SCHEMBL27739703 0.81 MEN1 (0.71) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL6915327 0.79 ALDH1A1 (0.62) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL8714704 0.79 ALDH1A1 (0.62) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL6908824 0.79 ALDH1A1 (0.62) ALDH1A1CYP3A4MAPK1CA1CA2
SCHEMBL6915856 0.79 ALDH1A1 (0.62) ALDH1A1CYP3A4MAPK1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2785782-B1 UV-STABILIZED, GLASS-FIBER REINFORCED, FLAME-RETARDANT POLYCARBONATES FOR THE EE AND IT SECTOR COVESTRO DEUTSCHLAND AG (DE) 2016-11-02 EP claimed
EP-2525972-B1 FLAME-PROTECTED ARTICLE HAVING A HIGH LEVEL OF TRANSMISSION COVESTRO DEUTSCHLAND AG (DE) 2016-11-02 EP claimed
EP-2785783-B1 ETHYLENE-PROPYLENE-MALEIC ACID ANHYDRIDE COPOLYMER AS IMPACT MODIFIER IN GLASS-FIBER REINFORCED, FLAME-RETARDANT POLYCARBONATES FOR THE EE SECTOR COVESTRO DEUTSCHLAND AG (DE) 2016-09-28 EP claimed
EP-4524200-A1 TRANSPARENT POLYCARBONATE/POLYACRYLATE BLENDS Covestro Deutschland AG (DE) 2025-03-19 EP disclosed
EP-4499749-A1 POLYCARBONATE COMPOSITIONS HAVING A HIGH CTI Covestro Deutschland AG (DE) 2025-02-05 EP disclosed
EP-4500558-A1 EE DEVICE COMPRISING A COMPOSITE POLYCARBONATE ELEMENT HAVING HIGH CTI Covestro Deutschland AG (DE) 2025-02-05 EP disclosed
EP-3838979-B1 MELT POLYCARBONATE WITH IMPROVED OPTICAL PROPERTIES COVESTRO DEUTSCHLAND AG (DE) 2024-06-26 EP disclosed
EP-4381015-A1 POLYCARBONATE COMPOSITIONS HAVING A HIGH CTI Covestro Deutschland AG (DE) 2024-06-12 EP disclosed
EP-4355827-A1 FLAME-RETARDANT POLYCARBONATE COMPOSITIONS HAVING A HIGH CTI Covestro Deutschland AG (DE) 2024-04-24 EP disclosed
EP-4341340-A1 FLAME-RETARDANT COMPOSITION CONTAINING 0.040 TO 0.095 WT.% OF A FLAME RETARDANT Covestro Deutschland AG (DE) 2024-03-27 EP disclosed
EP-4341328-A1 REDUCING THE CONTENT OF SPECIFIC SALTS OF SULFONIC ACID DERIVATIVES, SULFONAMIDE DERIVATIVES OR SULFONIMIDE DERIVATIVES IN WASTEWATER Covestro Deutschland AG (DE) 2024-03-27 EP disclosed
WO-2004035672-A1 FLAMEPROOF POLYCARBONATES AND POLYESTER CARBONATES BAYER MATERIALSCIENCE AG (DE) 2004-04-29 WO disclosed
EP-1383829-A1 FLAME-RETARDANT, ANTI-STATIC POLYCARBONATE MOULDING COMPOUNDS Bayer Aktiengesellschaft (DE) 2004-01-28 EP disclosed
US-20020177643-A1 Flame-retardant polycarbonate molding compounds with anti-electrostatic properties BAYER AKTIENGESELLSCHAFT (DE) 2002-11-28 US disclosed
WO-2002083777-A1 FLAME-RETARDANT, ANTI-STATIC POLYCARBONATE MOULDING COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 2002-10-24 WO disclosed
US-5693697-A Flame-resistant polycarbonate moulding-compositions BAYER AKTIENGESELLSCHAFT (DE) 1997-12-02 US disclosed
EP-0712901-A2 Flame retardant polycarbonate moulding compositions BAYER AG (DE) 1996-05-22 EP disclosed
EP-0024331-B1 PROCESS FOR PREPARING FLAME-RESISTANT POLYCARBONATES BAYER AG (DE) 1983-05-25 EP disclosed
EP-0024331-A1 Process for preparing flame-resistant polycarbonates BAYER AG (DE) 1981-03-04 EP disclosed
US-4208489-A AN ALKALI METAL SALT AND A TETRAHALOGENOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1980-06-17 US disclosed