Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA3 | P07451 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 3/20 | 0.56 |
| ▸ | CA6 | P23280 | 3/20 | 0.56 |
| ▸ | CA5A | P35218 | 3/20 | 0.56 |
| ▸ | CA7 | P43166 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6913638 | 0.97 | ALDH1A1 (0.65) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL125763 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL6915327 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL8720142 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL6917664 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL6915856 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL6917676 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL8714704 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL6908824 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| SCHEMBL1655868 | 0.94 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114843405-A | Chlorine-containing organic potassium salt modified perovskite solar cell electron transport layer, perovskite solar cell and preparation method thereof | 武汉理工大学 | 2022-08-02 | — | — | CN | claimed |
| CN-112940432-B | Polymerizable monomer for dental material, composition, adhesive dental material, and kit | 三井化学株式会社 | 2022-12-30 | — | — | CN | disclosed |
| CN-107815354-B | Collar cleaner and preparation method thereof | 北京金鱼科技有限责任公司 | 2020-10-30 | — | — | CN | disclosed |
| US-20040249195-A1 | Lithium rho-diarylphosphinobenzenesulfonates, process for preparation of the same and use thereof | KURARAY CO., LTD. (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1405854-A1 | LITHIUM P-DIARYLPHOSPHINOBENZENESULFONATES, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF | KURARAY CO., LTD. (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-5744678-A | NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY | NIPPON OIL CO., LTD. (JP) | 1998-04-28 | — | — | US | disclosed |
| EP-0758563-A1 | OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT | NIPPON OIL COMPANY, LTD. (JP) | 1997-02-19 | — | — | EP | disclosed |
| US-4432987-A | PEDIATIC BACTERICIDE | PFIZER INC. (US) | 1984-02-21 | — | — | US | disclosed |
| US-4329417-A | OXIDIZERS AND QUATERNARY AMMONIUM SALTS, PHOSPHONIUM SALTS OR SULFONIUM SALTS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1982-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040249195-A1 | Lithium rho-diarylphosphinobenzenesulfonates, process for preparation of the same and use thereof | ROCK1, RHOA, ARHGDIA | PTGS1 247/4885PTGS2 1116/4885ALDH1A1 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.