SCHEMBL130321

SCHEMBL130321

SCCCCCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 10/20 0.59
MAOA P21397 1/20 0.56
MAOB P27338 2/20 0.54
MAPT P10636 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.50
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13606188 1.00 SIGMAR1 (0.59) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL13606190 1.00 SIGMAR1 (0.59) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL128294 1.00 SIGMAR1 (0.59) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL13606187 1.00 SIGMAR1 (0.59) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL15105416 1.00 SIGMAR1 (0.59) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL7646991 1.00 SIGMAR1 (0.59) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL9998889 1.00 SIGMAR1 (0.59) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL13606194 1.00 SIGMAR1 (0.59) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL15105362 1.00 SIGMAR1 (0.59) SIGMAR1MAOAMAOBMAPTRXFP1
SCHEMBL11510150 1.00 SIGMAR1 (0.59) SIGMAR1MAOAMAOBMAPTRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 341 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1558948-A1 SILOXANE OPTICAL WAVEGUIDES Polyset Company, Inc. (US) 2005-08-03 EP claimed
US-6832036-B2 Siloxane optical waveguides POLYSET COMPANY, INC. 2004-12-14 US claimed
US-20040076391-A1 Siloxane optical waveguides POLYSET CHEMICAL COMPANY INC. (US) 2004-04-22 US claimed
WO-2004034104-A1 SILOXANE OPTICAL WAVEGUIDES POLYSET COMPANY INC. (US) 2004-04-22 WO claimed
US-20240116075-A1 SUBSTRATE, SELECTIVE FILM DEPOSITION METHOD, DEPOSITION FILM OF ORGANIC MATTER, AND ORGANIC MATTER CENTRAL GLASS COMPANY, LIMITED (JP) 2024-04-11 US disclosed
CN-113149883-B Process for preparing pyrrole compounds 武田药品工业株式会社 2024-04-02 CN disclosed
EP-4287240-A1 SUBSTRATE, SELECTIVE FILM DEPOSITION METHOD, DEPOSITION FILM OF ORGANIC MATTER, AND ORGANIC MATTER Central Glass Company, Limited (JP) 2023-12-06 EP disclosed
US-20230322669-A1 METHOD FOR PRODUCING PYRROLE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-10-12 US disclosed
EP-4257577-A2 METHOD FOR PRODUCING PYRROLE COMPOUND Takeda Pharmaceutical Company Limited (JP) 2023-10-11 EP disclosed
CN-116438214-A Sealing material for organic EL display element, cured product thereof, and organic EL display device 三井化学株式会社 2023-07-14 CN disclosed
US-11649206-B2 Method for producing pyrrole compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-16 US disclosed
US-20230143246-A1 LIQUID PREPARATIONS OF AMINES AND ORGANIC ACIDS STABILIZED BY SALTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-11 US disclosed
EP-0214823-A2 Alkylamide derivatives with H2-receptor antagonistic and cytoprotective action FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) 1987-03-18 EP disclosed
US-4373073-A Process for the preparation of glycidyl ethers of monohydric or polyhydric phenols, the glycidyl ethers and use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-08 US disclosed
US-4237290-A ODORANTS, FLAVORINGS; REACTION OF A SULFONIUM SALT AND A MERCAPTAN GIVAUDAN CORPORATION (US) 1980-12-02 US disclosed
US-4188488-A ALKYLIMIDAZOLYL SUBSTITUENTS GIVAUDAN CORPORATION (US) 1980-02-12 US disclosed
US-4180672-A 2-Organothio-2-cyclopentenones, organothio-cyclopentanes derived therefrom TEIJIN LIMITED (JP) 1979-12-25 US disclosed
US-4170594-A Oxazolyl-alkyl-disulphides as flavorants GIVAUDAN CORPORATION (US) 1979-10-09 US disclosed
US-4130562-A Odorant or flavoring thiazolyl disulphides GIVAUDAN CORPORATION (US) 1978-12-19 US disclosed
US-3931058-A POLYGLYCIDYL COMPOUNDS, PROCESSES FOR THEIR MANUFACTURE AND USE CIBA-GEIGY AG (CH) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230143246-A1 LIQUID PREPARATIONS OF AMINES AND ORGANIC ACIDS STABILIZED BY SALTS OTC, SLC38A7, SRI SIGMAR1 248/4885MAOA 4/4885MAOB 8/4885
US-20230322669-A1 METHOD FOR PRODUCING PYRROLE COMPOUND HPD, PPOX, CBR3 SIGMAR1 3736/4885MAOA 231/4885MAOB 234/4885
US-11649206-B2 Method for producing pyrrole compound HPD, PPOX, CBR3 SIGMAR1 3736/4885MAOA 231/4885MAOB 234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.