SCHEMBL13034754

SCHEMBL13034754

COC(=O)c1cc(Cc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C(=O)OC)c2)ccc1NS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ FFAR4 Q5NUL3 2/20 0.60
▸ CYP2C9 P11712 2/20 0.56
▸ LMNA P02545 3/20 0.55
▸ PTGDR2 Q9Y5Y4 1/20 0.54
▸ METAP2 P50579 5/20 0.53
▸ HTT P42858 2/20 0.51
▸ CYP1A2 P05177 1/20 0.51
▸ TCF4 P15884 1/20 0.50
▸ CTNNB1 P35222 1/20 0.50
▸ TP53 P04637 1/20 0.50
▸ MAPT P10636 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ CCR9 P51686 2/20 0.49
▸ KDM4E B2RXH2 1/20 0.49
▸ GAA P10253 1/20 0.49
▸ HSD17B10 Q99714 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13034755 0.95 METAP2 (0.61) FFAR4CYP2C9LMNAPTGDR2METAP2
SCHEMBL13034756 0.92 FFAR4 (0.52) FFAR4CYP2C9LMNAPTGDR2METAP2
SCHEMBL13034736 0.87 METAP2 (0.53) FFAR4CYP2C9LMNAPTGDR2METAP2
SCHEMBL14087834 0.87 METAP2 (0.70) CYP2C9LMNAPTGDR2METAP2HTT
SCHEMBL13034765 0.85 LMNA (0.60) CYP2C9LMNAPTGDR2METAP2HTT
SCHEMBL3511869 0.84 FFAR4 (0.62) FFAR4CYP2C9LMNAMETAP2HTT
SCHEMBL14397339 0.83 METAP2 (0.48) FFAR4CYP2C9LMNAPTGDR2METAP2
SCHEMBL23200363 0.83 FFAR4 (0.65) FFAR4CYP2C9LMNAMETAP2HTT
SCHEMBL16628393 0.83 FFAR4 (0.61) FFAR4CYP2C9LMNAMETAP2HTT
SCHEMBL3512980 0.83 CYP2C9 (0.72) FFAR4CYP2C9LMNAMETAP2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100280268-A1 HOMOGENEOUS TIME RESOLVED FLUORESCENCE BASED TEST SYSTEM TIBOTEC PHARMACEUTICALS LTD. (IE) 2010-11-04 — — US disclosed
US-20100280268-A1 HOMOGENEOUS TIME RESOLVED FLUORESCENCE BASED TEST SYSTEM TIBOTEC PHARMACEUTICALS LTD. (IE) 2010-11-04 — — US disclosed
WO-2007113337-A1 A HOMOGENEOUS TIME RESOLVED FLUORESCENCE BASED TEST SYSTEM TIBOTEC PHARMACEUTICALS LTD. (IE) 2007-10-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100280268-A1 HOMOGENEOUS TIME RESOLVED FLUORESCENCE BASED TEST SYSTEM C1QBP, CD4, CHRM4 FFAR4 2485/4885CYP2C9 4489/4885LMNA 2367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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