SCHEMBL13034811

SCHEMBL13034811

CCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.66
NOD1 Q9Y239 9/20 0.58
FOLH1 Q04609 1/20 0.45
PLA2G10 O15496 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19879791 1.00 GLP1R (0.66) GLP1RNOD1FOLH1PLA2G10
SCHEMBL10046212 1.00 GLP1R (0.66) GLP1RNOD1FOLH1PLA2G10
SCHEMBL12981754 1.00 GLP1R (0.66) GLP1RNOD1FOLH1PLA2G10
SCHEMBL15896588 1.00 GLP1R (0.66) GLP1RNOD1FOLH1PLA2G10
SCHEMBL24983192 0.99 GLP1R (0.68) GLP1RNOD1FOLH1PLA2G10
SCHEMBL21754511 0.94 GLP1R (0.69) GLP1RNOD1
SCHEMBL16182576 0.94 GLP1R (0.72) GLP1RNOD1
SCHEMBL17244046 0.94 GLP1R (0.72) GLP1RNOD1
SCHEMBL16182577 0.94 GLP1R (0.72) GLP1RNOD1
SCHEMBL10315877 0.94 GLP1R (0.72) GLP1RNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023217744-A1 PRODRUGS OF GLP-1 POLYPEPTIDE AND USES THEREOF NOVO NORDISK A/S (DK) 2023-11-16 WO disclosed
US-11649269-B2 Bifunctional compounds comprising insulin peptides and EGF(A) peptides NOVO NORDISK A/S (DK) 2023-05-16 US disclosed
US-11649269-B2 Bifunctional compounds comprising insulin peptides and EGF(A) peptides NOVO NORDISK A/S (DK) 2023-05-16 US disclosed
US-9480753-B2 FGF21 derivatives with albumin binder A-B-C-D-E- and their use NOVO NORDISK A/S (DK) 2016-11-01 US disclosed
US-9480753-B2 FGF21 derivatives with albumin binder A-B-C-D-E- and their use NOVO NORDISK A/S (DK) 2016-11-01 US disclosed
US-9181305-B2 Exendin-4 peptide analogues SANOFI (FR) 2015-11-10 US disclosed
US-20130143798-A1 NOVEL GLUCAGON ANALOGUES NOVO NORDISK A/S (DK) 2013-06-06 US disclosed
US-20130096055-A1 LONG-ACTING Y2 RECEPTOR AGONISTS NOVO NORDISK A/S (DK) 2013-04-18 US disclosed
US-20100292133-A1 TRUNCATED GLP-1 DERIVATIES AND THEIR THERAPEUTICAL USE NOVO NORDISK A/S (DK) 2010-11-18 US disclosed
US-20100292133-A1 TRUNCATED GLP-1 DERIVATIES AND THEIR THERAPEUTICAL USE NOVO NORDISK A/S (DK) 2010-11-18 US disclosed
US-20100216715-A1 FGF21 Derivatives With Albumin Binder A-B-C-D-E- And Their Use NOVO NORDISK A/S (DK) 2010-08-26 US disclosed
US-20100216715-A1 FGF21 Derivatives With Albumin Binder A-B-C-D-E- And Their Use NOVO NORDISK A/S (DK) 2010-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130143798-A1 NOVEL GLUCAGON ANALOGUES GLP1R, GCG, IAPP GLP1R 1/4885NOD1 1083/4885FOLH1 251/4885
US-11649269-B2 Bifunctional compounds comprising insulin peptides and EGF(A) peptides IAPP, IGFBP1, IGFBP2 GLP1R 16/4885NOD1 2091/4885FOLH1 659/4885
US-20130096055-A1 LONG-ACTING Y2 RECEPTOR AGONISTS NPY2R, NPY1R, NPY5R GLP1R 5/4885NOD1 3136/4885FOLH1 1335/4885
US-20100216715-A1 FGF21 Derivatives With Albumin Binder A-B-C-D-E- And Their Use FABP1, FABP4, FGFR1 GLP1R 45/4885NOD1 1001/4885FOLH1 1037/4885
US-20100292133-A1 TRUNCATED GLP-1 DERIVATIES AND THEIR THERAPEUTICAL USE GLP1R, GIPR, IAPP GLP1R 1/4885NOD1 295/4885FOLH1 1672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.