Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 17/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 17/20 | 0.67 |
| ▸ | GAA | P10253 | 9/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | HPN | P05981 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13035691 | 0.84 | MEN1 (0.71) | MEN1KMT2AGAAPOLBNPC1 | |
| SCHEMBL12783883 | 0.80 | MEN1 (1.00) | MEN1KMT2AGAAPOLBNPC1 | |
| SCHEMBL13035723 | 0.80 | MEN1 (0.59) | MEN1KMT2AGAAPOLBNPC1 | |
| SCHEMBL2031646 | 0.76 | MEN1 (1.00) | MEN1KMT2AGAAPOLBNPC1 | |
| SCHEMBL14709216 | 0.76 | MEN1 (1.00) | MEN1KMT2AGAAPOLBNPC1 | |
| SCHEMBL13035685 | 0.75 | MEN1 (1.00) | MEN1KMT2AGAAPOLBNPC1 | |
| SCHEMBL14709352 | 0.73 | MEN1 (1.00) | MEN1KMT2AGAAPOLBNPC1 | |
| SCHEMBL11568646 | 0.71 | MEN1 (1.00) | MEN1KMT2AGAAPOLBNPC1 | |
| SCHEMBL11203146 | 0.70 | MEN1 (0.57) | MEN1KMT2AGAAPOLBNPC1 | |
| SCHEMBL13035693 | 0.69 | MEN1 (1.00) | MEN1KMT2AGAAPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297046-A1 | Compositions and Methods Related to Fructosamine-3-Kinase Inhibitors | DYNAMIS THERAPEUTICS, INC. (US) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297046-A1 | Compositions and Methods Related to Fructosamine-3-Kinase Inhibitors | FN3K, ROS1, FN3KRP | MEN1 4765/4885KMT2A 2677/4885GAA 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.