Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CD38 | P28907 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558930 | 0.84 | NOS2 (0.43) | ALDH1A1KMT2AKDM4EMEN1NOS2 | |
| SCHEMBL3559596 | 0.83 | NOS2 (0.42) | ALDH1A1KMT2AKDM4EMEN1NOS2 | |
| SCHEMBL3565421 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL3565426 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL25485897 | 0.78 | KDM4E (0.45) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL3563653 | 0.77 | NOS2 (0.46) | ALDH1A1KMT2AKDM4EMEN1NOS2 | |
| SCHEMBL13074178 | 0.77 | NOS2 (0.43) | NOS2CD38CYP1A2CYP2C19 | |
| SCHEMBL3573524 | 0.75 | NOS2 (0.46) | ALDH1A1KMT2AKDM4EMEN1MAPT | |
| SCHEMBL3559939 | 0.75 | NOS2 (0.46) | ALDH1A1KMT2AKDM4EMEN1NOS2 | |
| SCHEMBL3558712 | 0.75 | NOS2 (0.46) | ALDH1A1KMT2AKDM4EMEN1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825256-B2 | Inducible nitric oxide synthase dimerization inhibitors | KALYPSYS, INC. (US) | 2010-11-02 | — | — | US | disclosed |