Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2295299 | 0.90 | PAX8 (0.41) | PAX8LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL5326303 | 0.90 | PAX8 (0.41) | PAX8LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL3419152 | 0.84 | LMNA (0.39) | PAX8LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL3419233 | 0.84 | LMNA (0.39) | PAX8LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL3421053 | 0.84 | LMNA (0.39) | PAX8LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL3421254 | 0.83 | LMNA (0.38) | PAX8LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL3414678 | 0.83 | LMNA (0.38) | PAX8LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL3421343 | 0.83 | LMNA (0.38) | PAX8LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL3414706 | 0.83 | LMNA (0.38) | PAX8LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL3415637 | 0.83 | LMNA (0.38) | PAX8LMNAL3MBTL1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807383-B1 | FLAVOUR MODULATING SUBSTANCES | GIVAUDAN NEDERLAND SERVICES BV (NL) | 2011-11-30 | — | — | EP | disclosed |
| US-8053013-B2 | Flavour modulating substances | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2011-11-08 | — | — | US | disclosed |
| US-20070298151-A1 | Flavour Modulating Substances | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2007-12-27 | — | — | US | disclosed |
| EP-1807383-A2 | FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL B.V. (NL) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006046854-A2 | FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL B.V. (NL) | 2006-05-04 | — | — | WO | disclosed |