Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13077471 | 0.88 | GRIA1 (0.31) | ACACBACACA | |
| SCHEMBL13039853 | 0.88 | TSHR (0.32) | — | |
| SCHEMBL16556753 | 0.85 | ACACB (0.34) | ALDH1A1MAPTRECQLACACBACACA | |
| SCHEMBL16556749 | 0.83 | POLB (0.30) | — | |
| SCHEMBL13167975 | 0.83 | OPRM1 (0.39) | ALDH1A1MAPTRECQL | |
| SCHEMBL13076974 | 0.83 | PTGS2 (0.36) | — | |
| SCHEMBL13883680 | 0.82 | — | — | |
| SCHEMBL13039922 | 0.82 | — | — | |
| SCHEMBL13039868 | 0.82 | BACE1 (0.30) | BACE1 | |
| SCHEMBL12214979 | 0.81 | ACACB (0.36) | ALDH1A1MAPTRECQLACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435549-B2 | Halogen alkoxy spirocyclic tetramic and tetronic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-05-07 | — | — | US | disclosed |
| US-8435549-B2 | Halogen alkoxy spirocyclic tetramic and tetronic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-05-07 | — | — | US | disclosed |
| US-20100279873-A1 | Halogen Alkoxy Spirocyclic Tetramic and Tetronic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-11-04 | — | — | US | disclosed |
| US-20100279873-A1 | Halogen Alkoxy Spirocyclic Tetramic and Tetronic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279873-A1 | Halogen Alkoxy Spirocyclic Tetramic and Tetronic Acid Derivatives | KCNA5, KCNH1, KCNQ5 | ALDH1A1 2192/4885MAPT 4151/4885RECQL 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.