Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13688637 | 0.80 | ALDH1A1 (0.36) | ALDH1A1LMNACYP2C9CYP2C19TSHR | |
| SCHEMBL13688636 | 0.80 | MAPT (0.47) | MAPTGAATDP1ALDH1A1KDM4E | |
| SCHEMBL8241193 | 0.75 | MAPK13 (0.45) | MAPTGAATDP1ALDH1A1KDM4E | |
| SCHEMBL13920985 | 0.75 | MAPK13 (0.45) | MAPTGAATDP1ALDH1A1KDM4E | |
| SCHEMBL2541882 | 0.73 | MAPT (0.41) | MAPTGAATDP1ALDH1A1KDM4E | |
| SCHEMBL935996 | 0.73 | ALDH1A1 (0.50) | MAPTGAAALDH1A1KDM4ELMNA | |
| SCHEMBL12657206 | 0.72 | MAPK14 (0.41) | MAPTGAATDP1ALDH1A1KDM4E | |
| SCHEMBL11754542 | 0.72 | MAPT (0.50) | MAPTGAATDP1ALDH1A1KDM4E | |
| SCHEMBL6857358 | 0.70 | SMN1; SMN2 (0.42) | MAPTGAATDP1ALDH1A1KDM4E | |
| SCHEMBL19260400 | 0.66 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264016-A2 | A process for producing pure form form of 2-Methyl-4-(4-Methyl-1-Piperazinyl)-10h-thieno[2,3-B][1,5] benzodiazepine | Jubilant Organosys Limited (IN) | 2010-12-22 | — | — | EP | disclosed |
| US-20090221560-A1 | Pharmaceutical Formulation | ACTAVIS GROUP PTC EHF | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221560-A1 | Pharmaceutical Formulation | MC2R, SLC6A4, MC5R | MAPT 392/4885GAA 1981/4885TDP1 3531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.