SCHEMBL13041388

SCHEMBL13041388

COC(=O)C1C=CC(C)CC1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
PPM1B O75688 1/20 0.32
PTPN1 P18031 1/20 0.32
PPP1CC P36873 1/20 0.32
TP53 P04637 1/20 0.32
CYP2C19 P33261 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA7 P36544 1/20 0.31
CHRNA4 P43681 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
CYP1A2 P05177 1/20 0.30
HIF1A Q16665 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25600270 1.00 ALDH1A1 (0.33) ALDH1A1PPM1BPTPN1PPP1CCTP53
SCHEMBL818076 0.89 PPM1B (0.38) ALDH1A1PPM1BPTPN1PPP1CCTP53
SCHEMBL25499830 0.81 CHRNB2 (0.35) ALDH1A1CYP2C19CHRNB2CHRNB4CHRNA3
SCHEMBL22787511 0.81 CHRNB2 (0.35) ALDH1A1CYP2C19CHRNB2CHRNB4CHRNA3
SCHEMBL12795464 0.81 CHRNB2 (0.35) ALDH1A1CYP2C19CHRNB2CHRNB4CHRNA3
SCHEMBL13042109 0.81 PPM1B (0.41) ALDH1A1PPM1BPTPN1PPP1CCTP53
SCHEMBL19985166 0.81 CHRNB2 (0.35) ALDH1A1CYP2C19CHRNB2CHRNB4CHRNA3
SCHEMBL20562897 0.79 PPM1B (0.38) ALDH1A1PPM1BPTPN1PPP1CC
SCHEMBL25603107 0.78 MMP2 (0.33) PPM1BPTPN1PPP1CCTP53CYP1A2
SCHEMBL25603104 0.78 MMP2 (0.33) PPM1BPTPN1PPP1CCTP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018210828-A1 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2018-11-22 WO disclosed
WO-2010148049-A2 PREPARATION OF TRANS, TRANS MUCONIC ACID AND TRANS, TRANS MUCONATES DRATHS CORPORATION (US) 2010-12-23 WO disclosed