Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.47 |
| ▸ | HTR2A | P28223 | 12/20 | 0.47 |
| ▸ | HTR7 | P34969 | 12/20 | 0.47 |
| ▸ | HTR6 | P50406 | 12/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10253535 | 0.87 | OPRM1 (0.52) | HTR1AHTR2AHTR7HTR6OPRM1 | |
| SCHEMBL6636785 | 0.77 | HTR7 (0.56) | HTR1AHTR2AHTR7HTR6OPRM1 | |
| SCHEMBL26025784 | 0.76 | OPRM1 (0.56) | HTR1AHTR2AHTR7HTR6OPRM1 | |
| SCHEMBL6635126 | 0.76 | HTR1A (0.49) | HTR1AHTR2AHTR7HTR6OPRM1 | |
| SCHEMBL6635868 | 0.75 | HTR7 (0.60) | HTR1AHTR2AHTR7HTR6OPRM1 | |
| SCHEMBL6636447 | 0.75 | HTR7 (0.60) | HTR1AHTR2AHTR7HTR6OPRM1 | |
| SCHEMBL6638270 | 0.75 | HTR7 (0.60) | HTR1AHTR2AHTR7HTR6OPRM1 | |
| Hydrochloric Acid SCHEMBL6639494 | 0.74 | HTR7 (0.59) | HTR1AHTR2AHTR7HTR6OPRM1 | |
| SCHEMBL6635753 | 0.74 | HTR1A (0.53) | HTR1AHTR2AHTR7HTR6OPRM1 | |
| Hydrochloric Acid SCHEMBL6636962 | 0.74 | HTR7 (0.59) | HTR1AHTR2AHTR7HTR6OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280049-A1 | ANTAGONISTS OF PGD2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100280049-A1 | ANTAGONISTS OF PGD2 RECEPTORS | PTGDR2, PTGDR, LTB4R2 | HTR1A 880/4885HTR2A 339/4885HTR7 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.