Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17968066 | 0.80 | F7 (0.44) | HTTNOTUMF7F3SARM1 | |
| SCHEMBL13975668 | 0.77 | HTT (0.46) | HTTNOTUMKCNA5CYP3A4CYP2C9 | |
| SCHEMBL27624091 | 0.73 | HTT (0.57) | HTTALDH1A1NOTUMF7F3 | |
| SCHEMBL1577273 | 0.70 | NOTUM (0.50) | HTTALDH1A1NOTUMF7F3 | |
| SCHEMBL5633185 | 0.70 | F7 (0.52) | HTTALDH1A1NOTUMF7F3 | |
| SCHEMBL6671752 | 0.69 | HTT (0.65) | HTTALDH1A1NOTUMKCNA5CYP3A4 | |
| Hydrochloric Acid SCHEMBL17785084 | 0.69 | NOTUM (0.49) | HTTALDH1A1NOTUMF7F3 | |
| SCHEMBL27837975 | 0.69 | ALDH1A1 (0.56) | HTTALDH1A1NOTUMKCNA5GAA | |
| SCHEMBL1850567 | 0.69 | HTT (0.46) | HTTALDH1A1NOTUMKCNA5CYP3A4 | |
| SCHEMBL8704299 | 0.68 | MTNR1A (0.43) | HTTALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258399-A2 | Multivalent VLA-4 antagonists comprising polymer moieties | Elan Pharmaceuticals Inc. (US) | 2010-12-08 | — | — | EP | disclosed |