Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.38 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935846 | 0.80 | PPARA (0.50) | SRD5A2PPARAPPARDMAOBPPARG | |
| SCHEMBL13205914 | 0.79 | HDAC1 (0.41) | SRD5A2PPARAPPARDMAOBPPARG | |
| SCHEMBL28274086 | 0.72 | KDM4E (0.51) | SRD5A2MAOBKDM4E | |
| SCHEMBL2985001 | 0.68 | SRD5A2 (0.40) | SRD5A2PPARAPPARG | |
| SCHEMBL11551303 | 0.67 | PPARA (0.68) | SRD5A2PPARAPPARDPPARG | |
| SCHEMBL8935661 | 0.66 | SLC16A3 (0.46) | PPARAMAOBPPARGKDM4ESLC16A3 | |
| SCHEMBL2981014 | 0.66 | ALDH1A1 (0.44) | SRD5A2 | |
| SCHEMBL883026 | 0.64 | SLC16A3 (0.55) | PPARAPPARDPPARGSLC16A3SLC16A1 | |
| SCHEMBL27932511 | 0.64 | SRD5A2 (0.86) | SRD5A2MAOB | |
| SCHEMBL648641 | 0.64 | SRD5A2 (0.83) | SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286144-A1 | HETEROARYL DERIVATIVES | TAKAHASHI YOKO | 2010-11-11 | — | — | US | disclosed |
| US-20100286144-A1 | HETEROARYL DERIVATIVES | TAKAHASHI YOKO | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286144-A1 | HETEROARYL DERIVATIVES | GPR119, SLC2A1, SLC2A4 | SRD5A2 110/4885PPARA 489/4885PPARD 801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.