SCHEMBL13044552

SCHEMBL13044552

O=C(O)CC(CO)(CC(=O)O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
CYP2D6 P10635 2/20 0.43
CYP2C19 P33261 2/20 0.43
HIF1A Q16665 2/20 0.43
TSHR P16473 1/20 0.43
HMGCR P04035 1/20 0.39
CHRM1 P11229 1/20 0.39
TBXA2R P21731 1/20 0.39
ADRA1A P35348 1/20 0.39
ACLY P53396 3/20 0.37
CPT2 P23786 2/20 0.36
KDM4E B2RXH2 1/20 0.33
FFAR1 O14842 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALOX15 P16050 1/20 0.32
LDHA P00338 1/20 0.30
SRR Q9GZT4 1/20 0.30
LMNA P02545 1/20 0.30
ALKBH5 Q6P6C2 1/20 0.30
SUCNR1 Q9BXA5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9747466 0.94 ALDH1A1 (0.46) ALDH1A1CYP2D6CYP2C19HIF1ATSHR
SCHEMBL2446996 0.84 ALDH1A1 (0.53) ALDH1A1CYP2D6CYP2C19HIF1ATSHR
SCHEMBL176385 0.81 ALDH1A1 (0.35) ALDH1A1CYP2D6CYP2C19HIF1ATSHR
Cyclohexane SCHEMBL5943434 0.79 CYP2D6 (0.38) ALDH1A1CYP2D6CYP2C19HIF1ATSHR
SCHEMBL1049552 0.78 ALDH1A1 (0.42) ALDH1A1CYP2D6CYP2C19HIF1ATSHR
SCHEMBL6394238 0.78 ALDH1A1 (0.33) ALDH1A1CYP2D6CYP2C19HIF1ATSHR
Chloroform SCHEMBL6213016 0.78 CYP2D6 (0.37) ALDH1A1CYP2D6CYP2C19HIF1ATSHR
SCHEMBL28249553 0.76 ALDH1A1 (0.40) ALDH1A1CYP2D6CYP2C19HIF1ATSHR
SCHEMBL833074 0.75 ARG1 (0.32) ALDH1A1TSHRACLY
SCHEMBL7415392 0.75 TDP1 (0.44) ALDH1A1TSHRCPT2FFAR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286462-A1 Apparati and Method for Remediating Biologically Active Particles Araba L.L.C. (US) 2010-11-11 US disclosed