SCHEMBL1049552

SCHEMBL1049552

O=C(O)CC(CCO)(CCO)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
CYP2D6 P10635 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
HMGCR P04035 1/20 0.36
CHRM1 P11229 1/20 0.36
TBXA2R P21731 1/20 0.36
ADRA1A P35348 1/20 0.36
CPT2 P23786 2/20 0.36
FFAR1 O14842 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ACLY P53396 3/20 0.34
CAMK2A Q9UQM7 1/20 0.32
ARG1 P05089 1/20 0.31
ARG2 P78540 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48924 0.86 CYP2D6 (0.39) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL6859283 0.83 FFAR1 (0.41) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL5163591 0.83 ARG2 (0.35) ALDH1A1TSHRCAMK2AARG1ARG2
SCHEMBL2446996 0.80 ALDH1A1 (0.53) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL13044552 0.78 ALDH1A1 (0.46) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL9747466 0.78 ALDH1A1 (0.46) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL3080191 0.78 ARG1 (0.33) ARG1ARG2
SCHEMBL11798815 0.77 ALDH1A1 (0.40) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL209594 0.77 ALDH1A1 (0.40) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL2138066 0.77 CYP2D6 (0.44) ALDH1A1CYP2D6TSHRCYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111432836-A Therapeutic protein compositions and methods of making and using same 转矩医疗股份有限公司 2020-07-17 CN disclosed
US-9296877-B2 Polymer film, retardation film, polarizing plate, liquid crystal display, and compound FUJIFILM CORPORATION (JP) 2016-03-29 US disclosed
US-20140363588-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND FUJIFILM CORPORATION (JP) 2014-12-11 US disclosed
US-20140053755-A1 Cellulose Acylate Film, Retardation Film, Polarizer and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2014-02-27 US disclosed
US-20130216733-A1 OPTICAL FILM AND ITS PRODUCTION METHOD, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-08-22 US disclosed
US-8465673-B2 Humidity dependence improver for polymer film, polymer film, protective film for polarizer, retardation film, polarizer, and liquid crystal display device FUJIFILM CORPORATION (JP) 2013-06-18 US disclosed
US-20130027634-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-01-31 US disclosed
US-8293341-B2 Cellulose ester film, retardation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-10-23 US disclosed
US-8263195-B2 Cellulose ester film, optically compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-09-11 US disclosed
US-20120204757-A1 Cellulose Acylate Film, Retardation Film, Polarizer and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2012-08-16 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110001904-A1 CELLULOSE ESTER FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-01-06 US disclosed
US-20110001907-A1 CELLULOSE ESTER FILM, RETARDATION FILM USING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-01-06 US disclosed
US-20100308264-A1 CELLULOSE ESTER FILM, OPTICALLY COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100055355-A1 Cellulose Acylate Film, Optical Compensation Film, Polarizing Plate, and Liquid-Crystal Display Device FUJIFILM CORPORATION (JP) 2010-03-04 US disclosed
US-20090286016-A1 CELLULOSE ESTER FILM, RETARDATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-19 US disclosed
EP-0345719-B1 COMPOUNDS CONTAINING AT LEAST THREE FUNCTIONAL ESTER GROUPS, AND PROCESS FOR THEIR PREPARATION Chemische Fabrik Stockhausen GmbH (DE) 1993-09-29 EP disclosed
US-5177249-A Dicarboxylic acid monoester plus epoxide CHEMISCHE FABRIK STOCKHAUSEN GMBH (DE) 1993-01-05 US disclosed
EP-0420884-A1 COMPOUNDS CONTAINING AT LEAST THREE FUNCTIONAL ESTER GROUPS AND PROCESS FOR PRODUCING THEM Chemische Fabrik Stockhausen GmbH (DE) 1991-04-10 EP disclosed
WO-1989012040-A1 COMPOUNDS CONTAINING AT LEAST THREE FUNCTIONAL ESTER GROUPS AND PROCESS FOR PRODUCING THEM CHEMISCHE FABRIK STOCKHAUSEN GMBH (DE) 1989-12-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140363588-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND COMPOUND PYM1, CNKSR1, MYB ALDH1A1 3710/4885CYP2D6 3527/4885TSHR 778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.