Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.49 |
| ▸ | GABRP | O00591 | 3/20 | 0.47 |
| ▸ | GABRD | O14764 | 3/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.47 |
| ▸ | GABRE | P78334 | 3/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13043506 | 0.87 | RAB9A (0.71) | RAB9ANPC1MEN1KMT2ANR4A2 | |
| SCHEMBL13044594 | 0.85 | RAB9A (0.73) | RAB9ANPC1MEN1KMT2AGABRP | |
| SCHEMBL13044035 | 0.84 | RAB9A (0.58) | RAB9ANPC1MEN1KMT2ANR4A2 | |
| SCHEMBL3718548 | 0.83 | GABRP (0.58) | RAB9ANPC1MEN1KMT2ANR4A2 | |
| SCHEMBL13044025 | 0.83 | NHERF1 (0.53) | RAB9ANPC1MEN1KMT2ANR4A2 | |
| SCHEMBL11924596 | 0.81 | RAB9A (0.73) | RAB9ANPC1MEN1KMT2AGABRP | |
| SCHEMBL13044607 | 0.81 | GABRP (0.56) | RAB9ANPC1MEN1KMT2ANR4A2 | |
| SCHEMBL13043507 | 0.79 | NPC1 (0.71) | RAB9ANPC1MEN1KMT2ANR4A2 | |
| SCHEMBL13043196 | 0.77 | RAB9A (0.51) | RAB9ANPC1MEN1KMT2ANR4A2 | |
| SCHEMBL13044604 | 0.77 | NR4A2 (0.60) | RAB9ANPC1MEN1KMT2ANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139982-A1 | INDOLE DERIVATIVES FOR THE STIMULATION OF STEM CELL PROLIFERATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2010-12-09 | — | — | WO | disclosed |