Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 17/20 | 0.70 |
| ▸ | SULT1A1 | P50225 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13904152 | 0.93 | APP (0.67) | APPSULT1A1MAPTSMN1; SMN2 | |
| SCHEMBL29385461 | 0.88 | APP (0.72) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL10032146 | 0.88 | APP (0.72) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL10032131 | 0.86 | APP (0.73) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL10311767 | 0.86 | APP (0.73) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL13015366 | 0.85 | APP (0.67) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL10032132 | 0.85 | APP (0.69) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL10311787 | 0.85 | APP (0.63) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL13015369 | 0.85 | APP (0.67) | APPSULT1A1MAPTTP53THRB | |
| SCHEMBL11996726 | 0.84 | APP (0.69) | APPSULT1A1MAPTTP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292478-A1 | PROCESS OF PREPARING A RADIOACTIVE COMPOUND CONTAINING A FLUORINE-18 ISOTOPE | GACHON UNIVERSITY OF MEDICINE & SCIENCE INDUSTRY- ACADEMIC COOPERATION FOUNDATION (KR) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292478-A1 | PROCESS OF PREPARING A RADIOACTIVE COMPOUND CONTAINING A FLUORINE-18 ISOTOPE | UHRF1, FTO, AGO2 | APP 1571/4885SULT1A1 74/4885MAPT 2773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.