SCHEMBL29385461

SCHEMBL29385461

Oc1ccc2nc(-c3ccc(NCCF)cc3)sc2c1

nearest known ligand 0.72

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
APP P05067 17/20 0.72
SULT1A1 P50225 4/20 0.67
MAPT P10636 2/20 0.67
TP53 P04637 1/20 0.53
THRB P10828 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032146 1.00 APP (0.72) APPSULT1A1MAPTTP53THRB
SCHEMBL10032131 0.92 APP (0.73) APPSULT1A1MAPTTP53THRB
SCHEMBL10311767 0.92 APP (0.73) APPSULT1A1MAPTTP53THRB
SCHEMBL10032132 0.91 APP (0.69) APPSULT1A1MAPTTP53THRB
SCHEMBL16256416 0.89 APP (0.66) APPSULT1A1MAPTTP53THRB
SCHEMBL13045481 0.88 APP (0.70) APPSULT1A1MAPTTP53THRB
SCHEMBL16256417 0.88 APP (0.61) APPSULT1A1MAPTTP53THRB
SCHEMBL24133691 0.87 APP (0.60) APPSULT1A1MAPTTP53THRB
SCHEMBL10311787 0.86 APP (0.63) APPSULT1A1MAPTTP53THRB
SCHEMBL13904152 0.86 APP (0.67) APPSULT1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062607-A1 TWO-DIMENSIONAL LATTICE CONFINED SINGLE-MOLECULE-LIKE AGGREGATES PURDUE RESEARCH FOUNDATION (US) 2026-03-05 US claimed
EP-4652549-A1 APPARATUS FOR A TILED LEARNING PROCESSING ELEMENT AND ARCHITECTURE Mignon Technologies Ltd (GB) 2025-11-26 EP claimed
CN-110892267-B System and method for real-time glycan determination of a sample 安进公司 2024-08-09 CN claimed
WO-2024153922-A1 APPARATUS FOR A TILED LEARNING PROCESSING ELEMENT AND ARCHITECTURE UNIVERSITY OF NEWCASTLE UPON TYNE (GB) 2024-07-25 WO claimed
WO-2026099341-A1 BIOCONTAINMENT OF UNWANTED ENGINEERED CELLS USING NON-NATURAL AMINO ACIDS SNIPR BIOME APS (DK) 2026-05-15 WO disclosed
CN-122036906-A Recombinant protein of novel cytokine for promoting collagen regeneration, and preparation method and application thereof 四川大学华西口腔医院 2026-05-15 CN disclosed
EP-4739777-A1 TRANSMISSIBLE ELEMENTS COMPRISING PATHWAY MODIFICATION SYSTEMS AND EXOGENOUS NUCLEIC ACIDS FOR THE PRODUCTION OF MOLECULES OF INTEREST SNIPR Biome ApS (DK) 2026-05-13 EP disclosed
US-12612395-B2 Rocaglate derivatives and uses thereof TRUSTEES OF BOSTON UNIVERSITY (US) 2026-04-28 US disclosed
US-20260109991-A1 PHAGE-DERIVED PARTICLES FOR IN SITU DELIVERY OF DNA PAYLOAD INTO C. ACNES POPULATION ELIGO BIOSCIENCE (FR) 2026-04-23 US disclosed
US-12577275-B2 Hydrophobic interaction chromatography carrier and protein purification method JNC CORPORATION (JP) 2026-03-17 US disclosed
US-20260062607-A1 TWO-DIMENSIONAL LATTICE CONFINED SINGLE-MOLECULE-LIKE AGGREGATES PURDUE RESEARCH FOUNDATION (US) 2026-03-05 US disclosed
EP-4677075-A2 TARGETING CELLS IN STRESSED GROWING CONDITIONS SNIPR Biome ApS (DK) 2026-01-14 EP disclosed
WO-2022096590-A1 PHAGE-DERIVED PARTICLES FOR IN SITU DELIVERY OF DNA PAYLOAD INTO C. ACNES POPULATION ELIGO BIOSCIENCE (FR) 2022-05-12 WO disclosed
WO-2022096596-A1 CUTIBACTERIUM ACNES RECOMBINANT PHAGES, METHOD OF PRODUCTION AND USES THEREOF ELIGO BIOSCIENCE (FR) 2022-05-12 WO disclosed
US-20220135987-A1 CUTIBACTERIUM ACNES RECOMBINANT PHAGES, METHOD OF PRODUCTION AND USES THEREOF ELIGO BIOSCIENCE (FR) 2022-05-05 US disclosed
US-20220135986-A1 PHAGE-DERIVED PARTICLES FOR IN SITU DELIVERY OF DNA PAYLOAD INTO C. ACNES POPULATION ELIGO BIOSCIENCE (FR) 2022-05-05 US disclosed
CN-114372543-A RFID (radio frequency identification device) indoor multi-target 3D (three-dimensional) positioning system and method based on carrier phase 重庆邮电大学 2022-04-19 CN disclosed
US-11279708-B2 Amidino- and amino-rocaglates as novel translation inhibitors and anticancer agents TRUSTEES OF BOSTON UNIVERSITY (US) 2022-03-22 US disclosed
US-11249026-B2 Use of raman spectroscopy to monitor culture medium BIOGEN MA INC. (US) 2022-02-15 US disclosed
US-20220033830-A1 FUNCTIONALIZATION OF ENDOGENOUS BACTERIA TRUSTEES OF BOSTON UNIVERSITY (US) 2022-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11279708-B2 Amidino- and amino-rocaglates as novel translation inhibitors and anticancer agents EIF2B3, EIF4EBP1, G3BP1 APP 2369/4885SULT1A1 3929/4885MAPT 3972/4885
US-20260062607-A1 TWO-DIMENSIONAL LATTICE CONFINED SINGLE-MOLECULE-LIKE AGGREGATES BLM, MEF2D, SNCA APP 3405/4885SULT1A1 3552/4885MAPT 144/4885
US-12612395-B2 Rocaglate derivatives and uses thereof GLRB, SRR, HCAR3 APP 3988/4885SULT1A1 174/4885MAPT 4722/4885
US-12577275-B2 Hydrophobic interaction chromatography carrier and protein purification method SSB, MAX, CD81 APP 863/4885SULT1A1 4777/4885MAPT 2490/4885
US-20260109991-A1 PHAGE-DERIVED PARTICLES FOR IN SITU DELIVERY OF DNA PAYLOAD INTO C. ACNES POPULATION CUTA, STAT3, POLL APP 562/4885SULT1A1 3613/4885MAPT 2996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.