SCHEMBL13045843

SCHEMBL13045843

O=C(O)c1cc(-n2cccn2)ccc1-c1c2ccc(=O)cc-2oc2cc(O)ccc12

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.63
▸ L3MBTL1 Q9Y468 1/20 0.63
▸ MEN1 O00255 2/20 0.54
▸ POLB P06746 2/20 0.54
▸ KMT2A Q03164 2/20 0.54
▸ ATM Q13315 1/20 0.54
▸ PLEC Q15149 1/20 0.54
▸ ALPL P05186 1/20 0.54
▸ ALPI P09923 1/20 0.54
▸ ALPG P10696 1/20 0.54
▸ CA9 Q16790 16/20 0.53
▸ CA1 P00915 14/20 0.53
▸ CA2 P00918 14/20 0.53
▸ DNASE1L3 Q13609 1/20 0.51
▸ PRMT1 Q99873 1/20 0.51
▸ CA12 O43570 5/20 0.51
▸ CA14 Q9ULX7 4/20 0.50
▸ CA7 P43166 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1103795 0.82 USP2 (0.69) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL22651493 0.81 USP2 (0.68) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL16283416 0.80 USP2 (0.67) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL29591827 0.80 USP2 (0.76) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL107875 0.80 USP2 (0.76) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL29781098 0.80 USP2 (0.76) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL7591292 0.79 USP2 (0.74) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL1437042 0.79 USP2 (0.78) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL8451224 0.79 USP2 (0.74) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL20254033 0.79 USP2 (0.77) USP2L3MBTL1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10006918-B2 Fluorogenic hydrazine-substituted compounds Life Technologies Corporation (US) 2018-06-26 — — US disclosed
US-20160356782-A1 FLUOROGENIC HYDRAZINE-SUBSTITUTED COMPOUNDS Life Technologies Corporation 2016-12-08 — — US disclosed
US-9389183-B2 Fluorogenic hydrazine-substituted compounds Life Technologies Corporation (US) 2016-07-12 — — US disclosed
US-8772487-B2 Fluorogenic hydrazine-substituted compounds Life Technologies Corporation (US) 2014-07-08 — — US disclosed
US-20130288911-A1 FLUOROGENIC HYDRAZINE-SUBSTITUTED COMPOUNDS Life Technologies Corporation 2013-10-31 — — US disclosed
US-20100291547-A1 FLUOROGENIC HYDRAZINE-SUBSTITUTED COMPOUNDS Life Technologies Corporation (US) 2010-11-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100291547-A1 FLUOROGENIC HYDRAZINE-SUBSTITUTED COMPOUNDS ALDH2, ALDH1A2, HLCS USP2 3504/4885L3MBTL1 1484/4885MEN1 2294/4885
US-10006918-B2 Fluorogenic hydrazine-substituted compounds ALDH2, ALDH1A2, HLCS USP2 3504/4885L3MBTL1 1484/4885MEN1 2294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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