Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15355554 | 0.93 | MEN1 (0.48) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL20305836 | 0.91 | ABCB1 (0.47) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL19494880 | 0.87 | ABCB1 (0.45) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL10205417 | 0.85 | USP2 (0.58) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL20305834 | 0.84 | P2RY6 (0.49) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL13771828 | 0.83 | ALDH1A1 (0.44) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL19494844 | 0.80 | AR (0.46) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL19495008 | 0.79 | ABCB1 (0.42) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL12582030 | 0.79 | KDM4E (0.49) | ABCB1USP2CFTRPAX8ATM | |
| SCHEMBL10082262 | 0.77 | MEN1 (0.48) | ABCB1USP2CFTRPAX8ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160356782-A1 | FLUOROGENIC HYDRAZINE-SUBSTITUTED COMPOUNDS | Life Technologies Corporation | 2016-12-08 | — | — | US | disclosed |
| US-9389183-B2 | Fluorogenic hydrazine-substituted compounds | Life Technologies Corporation (US) | 2016-07-12 | — | — | US | disclosed |
| US-8772487-B2 | Fluorogenic hydrazine-substituted compounds | Life Technologies Corporation (US) | 2014-07-08 | — | — | US | disclosed |
| US-20130288911-A1 | FLUOROGENIC HYDRAZINE-SUBSTITUTED COMPOUNDS | Life Technologies Corporation | 2013-10-31 | — | — | US | disclosed |
| US-20100291547-A1 | FLUOROGENIC HYDRAZINE-SUBSTITUTED COMPOUNDS | Life Technologies Corporation (US) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100291547-A1 | FLUOROGENIC HYDRAZINE-SUBSTITUTED COMPOUNDS | ALDH2, ALDH1A2, HLCS | ABCB1 3051/4885USP2 3504/4885CFTR 1497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.