SCHEMBL1304633

SCHEMBL1304633

CC1=C(C)C(C)(C)C([Ru]Cl)=C1C.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
DRD1 P21728 2/20 0.34
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3007177 0.89
SCHEMBL3001866 0.89 ESR1 (0.38) ESR1ESR2
SCHEMBL6788115 0.83
SCHEMBL3700202 0.80 CTSD (0.31)
SCHEMBL2993565 0.75 CYP3A4 (0.41) CYP3A4TDP1DRD1ESR1ESR2
SCHEMBL2998095 0.74
SCHEMBL2998015 0.74
SCHEMBL18605788 0.74 CYP3A4 (0.44) CYP3A4TDP1DRD1ESR1ESR2
SCHEMBL2542068 0.73
Hydrochloric Acid SCHEMBL3662739 0.72 CYP3A4 (0.43) CYP3A4TDP1DRD1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250084100-A1 METHOD FOR PREPARING NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, AND INTERMEDIATE AND USE OF COMPOUND APPLIED PHARMACEUTICAL SCIENCE, INC. (CN) 2025-03-13 US claimed
EP-4368621-A1 METHOD FOR PREPARING NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, AND INTERMEDIATE AND USE OF COMPOUND Applied Pharmaceutical Science, Inc. (CN) 2024-05-15 EP claimed
US-12595258-B2 Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment or amelioration of cancer TOLREMO THERAPEUTICS AG (CH) 2026-04-07 US disclosed
US-20250243191-A1 HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OR AMELIORATION OF CANCER TOLREMO THERAPEUTICS AG (CH) 2025-07-31 US disclosed
WO-2025120669-A1 A LENTICULE, METHOD OF PREPARATION AND IMPLEMENTATIONS THEREOF PANDORUM TECHNOLOGIES PRIVATE LIMITED (IN) 2025-06-12 WO disclosed
US-20250084100-A1 METHOD FOR PREPARING NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, AND INTERMEDIATE AND USE OF COMPOUND APPLIED PHARMACEUTICAL SCIENCE, INC. (CN) 2025-03-13 US disclosed
US-20250057815-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS BRISTOL MYERS SQUIBB CO (US) 2025-02-20 US disclosed
US-20250049970-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-02-13 US disclosed
US-20250034210-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-01-30 US disclosed
US-20250011368-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-01-09 US disclosed
US-20240327394-A1 HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OR AMELIORATION OF CANCER TOLREMO THERAPEUTICS AG (CH) 2024-10-03 US disclosed
EP-1903394-A1 Resist composition, resin for use in the resist composition, and pattern-forming method using the resist composition FUJIFILM Corporation (JP) 2008-03-26 EP disclosed
EP-1847553-A1 METHOD FOR REMOVING METAL AND METHOD FOR PRODUCING POLYMER NIPPON SODA CO., LTD. (JP) 2007-10-24 EP disclosed
EP-1780224-A1 MULTIBRANCHED POLYMERS AND PROCESS FOR PRODUCTION THEREOF NIPPON SODA CO., LTD. (JP) 2007-05-02 EP disclosed
EP-1553117-B1 SOLID POLYMER ELECTROLYTE NIPPON SODA CO (JP) 2007-01-17 EP disclosed
US-20060223944-A1 Polar monomer-olefin copolymer and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED 2006-10-05 US disclosed
US-20060166136-A1 Positive resist composition for immersion exposure and pattern-forming method using the same FUJI PHOTO FILM CO., LTD. 2006-07-27 US disclosed
EP-1684119-A2 Positive resist composition for immersion exposure and pattern-forming method using the same FUJI PHOTO FILM CO., LTD. (JP) 2006-07-26 EP disclosed
US-20050256256-A1 Block polymer of polymethoxypolyethylene glycol monomethyl methacrylate and polystyrene; LiClO4 a lithium salt as electrolyte; living copolymerization, block polymerization; excellent thermal characteristics, physical characteristics, and ionic conductivity; secondary batteries NIPPON SODA CO., LTD (JP) 2005-11-17 US disclosed
EP-1553117-A1 SOLID POLYMER ELECTROLYTE NIPPON SODA CO., LTD. (JP) 2005-07-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595258-B2 Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment or amelioration of cancer SLC10A1, MAPT, SLC6A6 CYP3A4 606/4885TDP1 763/4885DRD1 4318/4885
US-20240327394-A1 HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OR AMELIORATION OF CANCER TP53, MAPT, SLC10A1 CYP3A4 99/4885TDP1 751/4885DRD1 3472/4885
US-20250049970-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF DLK1, DBNL, PDLIM5 CYP3A4 4882/4885TDP1 3564/4885DRD1 2629/4885
US-20250084100-A1 METHOD FOR PREPARING NITROGEN-CONTAINING POLYCYCLIC FUSED RING COMPOUND, AND INTERMEDIATE AND USE OF COMPOUND RANBP1, RANBP2, RAN CYP3A4 635/4885TDP1 4063/4885DRD1 665/4885
US-20250011368-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF DLK1, DBNL, PDCD1LG2 CYP3A4 4882/4885TDP1 3582/4885DRD1 2255/4885
US-20250057815-A1 CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACIDS AS LPA ANTAGONISTS LPAR3, LPAR1, LPAR2 CYP3A4 2036/4885TDP1 3121/4885DRD1 3978/4885
US-20250243191-A1 HETEROCYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OR AMELIORATION OF CANCER TP53, MAPT, SLC10A1 CYP3A4 99/4885TDP1 751/4885DRD1 3472/4885
US-20250034210-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF DLK1, DBNL, PDCD1LG2 CYP3A4 4882/4885TDP1 3582/4885DRD1 2255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.