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Sugi Predict / Targets / RANBP1

RANBP1

Ran-specific GTPase-activating protein · P43487 · RANBP1 on Sugi Atlas →

1,773 patent compounds predicted against RANBP1, 1,357 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Eltanexor Eltanexor (SCHEMBL16323699) 1.00 1/20
Eltanexor Eltanexor (SCHEMBL16323700) 1.00 1/20
Eltanexor Eltanexor (SCHEMBL16324809) 1.00 1/20
SCHEMBL16361454 SCHEMBL16361454 0.86 1/20
SCHEMBL17788773 SCHEMBL17788773 0.86 1/20
SCHEMBL17788774 SCHEMBL17788774 0.86 1/20
SCHEMBL16322954 SCHEMBL16322954 0.82 1/20
SCHEMBL16325038 SCHEMBL16325038 0.82 1/20
SCHEMBL16361568 SCHEMBL16361568 0.81 1/20
SCHEMBL16324901 SCHEMBL16324901 0.80 1/20
SCHEMBL16324903 SCHEMBL16324903 0.80 1/20
SCHEMBL17782103 SCHEMBL17782103 0.80 1/20
SCHEMBL17782104 SCHEMBL17782104 0.80 1/20
SCHEMBL16324430 SCHEMBL16324430 0.79 1/20
SCHEMBL16324435 SCHEMBL16324435 0.79 1/20
SCHEMBL16323808 SCHEMBL16323808 0.77 1/20
SCHEMBL16323810 SCHEMBL16323810 0.77 1/20
SCHEMBL16324426 SCHEMBL16324426 0.77 1/20
SCHEMBL16324427 SCHEMBL16324427 0.77 1/20
SCHEMBL16361442 SCHEMBL16361442 0.77 1/20

Clinical trials — most relevant to RANBP1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Systemic Therapy and Chemoradiation in Advanced Localised Pancreatic Cancer - 2 PHASE1/PHASE2COMPLETED
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Clinical Trial of SB-509 in Subjects With Amyotrophic Lateral Sclerosis (ALS) PHASE2COMPLETED
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients PHASE1/PHASE2COMPLETED
A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas PHASE2COMPLETED
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
A Clinical Study on the Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX Intolerance) or Temozolomide (TMZ) Combined With Orelabrutinib and Selinexor in Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma（SELINA） nanRECRUITING
Gait in Rare Diseases nanCOMPLETED
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML) nanCOMPLETED
Blood-based Biomarkers for the Prognosis of Sports Related Concussion nanCOMPLETED
Study of Proteins in Head and Neck Cancer Cells nanCOMPLETED
Genetics of Familial and Sporadic ALS nanCOMPLETED
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others nanRECRUITING
Genetic and Blood Biomarkers in Neurological and Neuromuscular Diseases nanCOMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Amyotrophic Lateral Sclerosis (ALS) Families Project nanRECRUITING
Pleiotropy and Mechanism of Peripheral Nerve Related Genes in the Progression of Amyotrophic Lateral Sclerosis nanUNKNOWN
Exploring the Genetics of Neuropathic Pain nanRECRUITING
Autophagy Bladder Cancer nanUNKNOWN
Genomic Translation for Amyotrophic Lateral Sclerosis Care nanCOMPLETED
Gene Analysis of Parkinson's Disease nanCOMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
Comparative 2-D Tumor Analysis in Familial Gliomas nanCOMPLETED
Collection of Blood Samples for DNA in Motor Neuron Disease nanCOMPLETED
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Amyotrophic Lateral Sclerosis (ALS) Tissue Donation Program nanCOMPLETED
Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a RANBP1 binder may also engage these)

ProteinNameSimilarity
P34022 — 1.000 P34022 →
Q3T0M7 — 1.000 Q3T0M7 →
Q09717 — 0.995 Q09717 →
P41920 — 0.993 P41920 →
P92985 — 0.987 P92985 →
Q8RWG8 — 0.986 Q8RWG8 →
Q9LMK7 — 0.986 Q9LMK7 →
Q54KD9 — 0.984 Q54KD9 →
P31669 — 0.973 P31669 →
P27008 — 0.969 P27008 →
P28048 — 0.968 P28048 →
P26446 — 0.966 P26446 →
Q43207 — 0.965 Q43207 →
SSB Lupus La protein 0.965 landscape →
P87058 — 0.965 P87058 →
Q7Q9C0 — 0.965 Q7Q9C0 →
Q9TRY0 — 0.964 Q9TRY0 →
P12262 — 0.964 P12262 →
Q3T093 — 0.964 Q3T093 →
Q26457 — 0.964 Q26457 →
Q4WPW2 — 0.964 Q4WPW2 →
P38205 — 0.964 P38205 →
Q69JW2 — 0.964 Q69JW2 →
P48598 — 0.963 P48598 →
P40796 — 0.963 P40796 →
Q6DET9 — 0.963 Q6DET9 →
Q5ZML4 — 0.963 Q5ZML4 →
P27124 — 0.963 P27124 →
Q99L45 — 0.963 Q99L45 →
Q95YJ5 — 0.963 Q95YJ5 →