Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | CRHBP | P24387 | 1/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.61 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.50 |
| ▸ | CDC7 | O00311 | 9/20 | 0.49 |
| ▸ | DBF4 | Q9UBU7 | 9/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885122 | 0.92 | MAPT (0.73) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL2886264 | 0.86 | TRPM8 (0.71) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL13046766 | 0.86 | CDC7 (0.67) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL2883597 | 0.83 | PTPN11 (0.69) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL2886595 | 0.83 | TRPM8 (0.71) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL27717711 | 0.83 | MAPT (0.70) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL1316673 | 0.83 | CDC7 (0.70) | MAPTTRPM8PTPN11CDC7DBF4 | |
| SCHEMBL4484447 | 0.82 | MAPT (0.76) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL4804421 | 0.82 | MAPT (0.76) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL4467429 | 0.81 | MAPT (0.74) | MAPTMEN1KMT2AKDM4EHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834030-B2 | Phenyl-[1,2,4]-oxadiazol-5-one derivatives, pharmaceutical compositions and therapeutic use thereof | SANOFI-AVENTIS (FR) | 2010-11-16 | — | — | US | disclosed |
| US-7834030-B2 | Phenyl-[1,2,4]-oxadiazol-5-one derivatives, pharmaceutical compositions and therapeutic use thereof | SANOFI-AVENTIS (FR) | 2010-11-16 | — | — | US | disclosed |
| US-20080262036-A1 | Phenyl-[1,2,4]-oxadiazol-5-one Derivatives, Pharmaceutical Compositions and Therapeutic Use Thereof | SANOFI-AVENTIS (FR) | 2008-10-23 | — | — | US | disclosed |
| US-20080262036-A1 | Phenyl-[1,2,4]-oxadiazol-5-one Derivatives, Pharmaceutical Compositions and Therapeutic Use Thereof | SANOFI-AVENTIS (FR) | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262036-A1 | Phenyl-[1,2,4]-oxadiazol-5-one Derivatives, Pharmaceutical Compositions and Therapeutic Use Thereof | GPR119, CPT1A, PC | MAPT 1432/4885MEN1 3782/4885KMT2A 4613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.