⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16388046 | 0.81 | RXFP1 (0.38) | — | |
| SCHEMBL8845215 | 0.81 | MAPT (0.50) | — | |
| SCHEMBL13446569 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL20623042 | 0.79 | L3MBTL1 (0.44) | — | |
| SCHEMBL13446573 | 0.76 | ABL1 (0.40) | — | |
| SCHEMBL13715797 | 0.73 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL13411743 | 0.72 | CDK2 (0.40) | — | |
| SCHEMBL13446690 | 0.71 | KDM4E (0.33) | — | |
| SCHEMBL13411799 | 0.70 | RAB9A (0.35) | — | |
| SCHEMBL13411740 | 0.70 | HTT (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210323960-A1 | FUSED TRI-CYCLIC COMPOUND AS PDE3/PDE4 DUAL INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2021-10-21 | — | — | US | disclosed |
| WO-2020011254-A1 | FUSED TRI-CYCLIC COMPOUND AS PDE3/PDE4 DUAL INHIBITOR | 正大天晴药业集团股份有限公司 | 2020-01-16 | — | — | WO | disclosed |
| US-20160239117-A1 | LAYERED BODY FOR TRANSPARENT CONDUCTIVE MEMBER, TRANSFER MATERIAL, TRANSPARENT CONDUCTIVE MEMBER, TOUCH PANEL AND PROCESS FOR PRODUCING SAME, AND TOUCH PANEL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2016-08-18 | — | — | US | disclosed |
| US-20160239117-A1 | LAYERED BODY FOR TRANSPARENT CONDUCTIVE MEMBER, TRANSFER MATERIAL, TRANSPARENT CONDUCTIVE MEMBER, TOUCH PANEL AND PROCESS FOR PRODUCING SAME, AND TOUCH PANEL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2016-08-18 | — | — | US | disclosed |
| WO-2010139483-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-12-09 | — | — | WO | disclosed |