⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30331251 | 0.92 | — | — | |
| SCHEMBL1628000 | 0.82 | — | — | |
| SCHEMBL17102937 | 0.82 | — | — | |
| SCHEMBL34680 | 0.82 | — | — | |
| SCHEMBL13599846 | 0.71 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL4651720 | 0.71 | FKBP5 (0.33) | — | |
| SCHEMBL6053394 | 0.71 | FKBP5 (0.33) | — | |
| SCHEMBL9577017 | 0.69 | FKBP5 (0.32) | — | |
| SCHEMBL13513149 | 0.67 | — | — | |
| SCHEMBL5918490 | 0.67 | FKBP5 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4643997-A | PROTECTIVE COATINGS; SUNSCREEN AGENTS | WELLA AKTIENGESELLSCHAFT (DE) | 1987-02-17 | — | — | US | claimed |
| EP-4720058-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | Casma Therapeutics, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024249291-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | CASMA THERAPEUTICS, INC. (US) | 2024-12-05 | — | — | WO | disclosed |
| US-20230365556-A1 | N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230365556-A1 | N-ACYL AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | US | disclosed |
| US-11673887-B2 | N-acyl amino acid compounds and methods of use | PLIANT THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-11673887-B2 | N-acyl amino acid compounds and methods of use | PLIANT THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| CN-112142586-B | Ketone or oxime compounds and herbicides | 日产化学株式会社 | 2023-05-09 | — | — | CN | disclosed |
| EP-4053097-A1 | KETONE COMPOUND AS HERBICIDE | Corteva Agriscience LLC (US) | 2022-09-07 | — | — | EP | disclosed |
| EP-3235799-B1 | OXIME COMPOUND AND HERBICIDE | NISSAN CHEMICAL CORP (JP) | 2022-02-23 | — | — | EP | disclosed |
| US-4665172-A | Process for producing heterocyclic compound having nitromethylene group as the side chain group | UBE INDUSTRIES, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4643997-A | PROTECTIVE COATINGS; SUNSCREEN AGENTS | WELLA AKTIENGESELLSCHAFT (DE) | 1987-02-17 | — | — | US | disclosed |
| US-4625025-A | Process for producing a 2H-1,3-thiazolidine, 2H-tetrahydro-1,3-thiazine, or 2H-hexahydro-1,3-thiazepine derivative substituted at the 2 position by a nitromethylene group derivative | UBE INDUSTRIES, LTD. (JP) | 1986-11-25 | — | — | US | disclosed |
| EP-0189972-A1 | Preparation of thiazine derivatives | FINE ORGANICS LIMITED (GB) | 1986-08-06 | — | — | EP | disclosed |
| US-4532322-A | Preparation of thiazine derivatives | FINE ORGANICS LIMITED (GB) | 1985-07-30 | — | — | US | disclosed |
| EP-0135803-A2 | Process for producing heterocyclic compounds having nitromethylene group as the side chain group | UBE INDUSTRIES, LTD. (JP) | 1985-04-03 | — | — | EP | disclosed |
| EP-0127413-A2 | Preparation of thiazine derivatives | FINE ORGANICS LIMITED (GB) | 1984-12-05 | — | — | EP | disclosed |
| EP-0115323-A2 | Process for producing heterocyclic compound having nitromethylene group as the side chain group | UBE INDUSTRIES, LTD. (JP) | 1984-08-08 | — | — | EP | disclosed |
| US-4031228-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anti-protozoal activity | SYNTEX (U.S.A.) INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-3962437-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-06-08 | — | — | US | disclosed |