Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17708232 | 0.96 | THRB (0.42) | THRBTHRATYMSACHESMN1; SMN2 | |
| SCHEMBL14173231 | 0.90 | THRB (0.39) | THRBTHRATYMSACHESMN1; SMN2 | |
| SCHEMBL13048704 | 0.81 | THRB (0.34) | THRBTHRATYMSSMN1; SMN2KDM4E | |
| SCHEMBL17842625 | 0.81 | POLB (0.38) | THRBTHRATYMSMAPTNPSR1 | |
| SCHEMBL27464291 | 0.79 | TSHR (0.46) | THRBTHRAACHESMN1; SMN2MAPT | |
| SCHEMBL39820 | 0.79 | L3MBTL1 (0.47) | THRBTHRATYMSSMN1; SMN2MAPT | |
| SCHEMBL30593911 | 0.79 | L3MBTL1 (0.47) | THRBTHRATYMSSMN1; SMN2MAPT | |
| SCHEMBL1696567 | 0.79 | THRB (0.47) | THRBTHRATYMSACHESMN1; SMN2 | |
| SCHEMBL16921467 | 0.79 | THRB (0.44) | THRBTHRASMN1; SMN2MAPTKDM4E | |
| SCHEMBL18352540 | 0.77 | TSHR (0.50) | SMN1; SMN2MAPTNPSR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7833690-B2 | Photoacid generators and lithographic resists comprising the same | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2010-11-16 | — | — | US | disclosed |