Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1743625 | 1.00 | CYP3A4 (0.38) | CYP3A4TDP1ALDH1A1ALOX15TSHR | |
| SCHEMBL289857 | 0.90 | CYP3A4 (0.45) | CYP3A4TDP1ALDH1A1ALOX15TSHR | |
| SCHEMBL28001639 | 0.88 | CYP3A4 (0.39) | CYP3A4TDP1ALDH1A1ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL31568007 | 0.87 | CYP3A4 (0.43) | CYP3A4TDP1ALDH1A1ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL31467528 | 0.87 | CYP3A4 (0.43) | CYP3A4TDP1ALDH1A1ALOX15TSHR | |
| SCHEMBL19093066 | 0.87 | CYP3A4 (0.43) | CYP3A4TDP1ALDH1A1ALOX15TSHR | |
| SCHEMBL18796532 | 0.87 | CYP3A4 (0.43) | CYP3A4TDP1ALDH1A1ALOX15TSHR | |
| SCHEMBL14696690 | 0.87 | CYP3A4 (0.43) | CYP3A4TDP1ALDH1A1ALOX15TSHR | |
| SCHEMBL3645144 | 0.87 | CYP3A4 (0.43) | CYP3A4TDP1ALDH1A1ALOX15TSHR | |
| Bromide SCHEMBL28700347 | 0.87 | CYP3A4 (0.43) | CYP3A4TDP1ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125395-A1 | PROCESS FOR THE PREPARATION OF TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS FOR USING THE SAME FOR THE TREATMENT OF CANCER | GENENTECH INC (US) | 2026-05-07 | — | — | US | claimed |
| CN-116199558-B | Large conjugated molecular material DHRP containing five-ring and seven-ring systems and preparation and application thereof | 中国科学院化学研究所 | 2025-05-23 | — | — | CN | claimed |
| CN-119978004-A | Water-stable 2-pyridine inner salt boron reagent, preparation method thereof and application thereof in coupling reaction | 苏州大学 | 2025-05-13 | — | — | CN | claimed |
| CN-113999249-B | Methods for preparing tricyclic PI3K inhibitor compounds and methods of treating cancer using the same | 基因泰克公司 | 2025-03-25 | — | — | CN | claimed |
| CN-119591541-A | Synthesis method of propidium bromide | 西安市儿童医院 | 2025-03-11 | — | — | CN | claimed |
| CN-119462485-A | Novel synthetic method of 4-aryl pyridine derivative | 淮阴师范学院 | 2025-02-18 | — | — | CN | claimed |
| CN-118026957-A | Three-component coupling method for aromatic trifluoroalkyl compound, conjugated olefin and nucleophilic reagent | 国科大杭州高等研究院 | 2024-05-14 | — | — | CN | claimed |
| CN-117820209-A | Preparation method of 4- [3- (cyclopropylmethoxy) -4- (difluoromethoxy) phenethyl ] pyridin-2-ol | 中国医学科学院药物研究所 | 2024-04-05 | — | — | CN | claimed |
| CN-117567455-A | Novel oxazolidinone compound and synthetic method and application thereof | 华创合成制药股份有限公司 | 2024-02-20 | — | — | CN | claimed |
| US-20230242550-A1 | PROCESS FOR THE PREPARATION OF TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS FOR USING THE SAME FOR THE TREATMENT OF CANCER | GENENTECH, INC. | 2023-08-03 | — | — | US | claimed |
| WO-2017072596-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LEDIPASVIR | OPTIMUS DRUGS (P) LTD (IN) | 2017-05-04 | — | — | WO | claimed |
| EP-2142496-B1 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | EXXONMOBIL RES & ENG CO (US) | 2013-04-17 | — | — | EP | claimed |
| EP-2144867-B1 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | EXXONMOBIL RES & ENG CO (US) | 2013-01-16 | — | — | EP | claimed |
| EP-2176216-B1 | METHODS FOR SYNTHESIZING 9-SUBSTITUTED MINOCYCLINE | PARATEK PHARM INNC (US) | 2012-04-25 | — | — | EP | claimed |
| US-20110230680-A1 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-09-22 | — | — | US | claimed |
| US-8017806-B2 | Lubricating compositions containing ashless catalytic antioxidant additives | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-09-13 | — | — | US | claimed |
| US-20090287022-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | PATIL ABHIMANYU O | 2009-11-19 | — | — | US | claimed |
| US-20080248984-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2008-10-09 | — | — | US | claimed |
| US-20080245336-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2008-10-09 | — | — | US | claimed |
| US-20070265178-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2007-11-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125395-A1 | PROCESS FOR THE PREPARATION OF TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS FOR USING THE SAME FOR THE TREATMENT OF CANCER | PIK3C2B, PIK3C2A, PIK3CA | CYP3A4 738/4885TDP1 1937/4885ALDH1A1 3642/4885 |
| US-20080245336-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | GPX1, GPX4, SOD1 | CYP3A4 2208/4885TDP1 391/4885ALDH1A1 51/4885 |
| US-20080248984-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | GPX1, SOD1, CAT | CYP3A4 2453/4885TDP1 479/4885ALDH1A1 60/4885 |
| US-20230242550-A1 | PROCESS FOR THE PREPARATION OF TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS FOR USING THE SAME FOR THE TREATMENT OF CANCER | PIK3CA, PIK3CD, PIK3CB | CYP3A4 662/4885TDP1 508/4885ALDH1A1 4087/4885 |
| US-20070265178-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | GPX4, SOD1, GPX1 | CYP3A4 1131/4885TDP1 575/4885ALDH1A1 81/4885 |
| US-20090287022-A1 | Lubricating compositions containing ashless catalytic antioxidant additives | GPX1, GPX4, SOD1 | CYP3A4 2208/4885TDP1 391/4885ALDH1A1 51/4885 |
| US-20110230680-A1 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | GPX4, SOD1, GPX1 | CYP3A4 947/4885TDP1 507/4885ALDH1A1 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.