Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.60 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.60 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.60 |
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.57 |
| ▸ | RRM1 | P23921 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13049180 | 0.88 | KMT2A (0.65) | GNAI3GNAO1GNAI1NOD1RRM1 | |
| SCHEMBL13049190 | 0.88 | NOD1 (0.61) | NOD1KMT2A | |
| SCHEMBL411636 | 0.87 | NOD1 (0.53) | GNAI3GNAO1GNAI1NOD1TLR2 | |
| SCHEMBL444217 | 0.87 | NOD1 (0.53) | GNAI3GNAO1GNAI1NOD1TLR2 | |
| SCHEMBL906115 | 0.87 | NOD1 (0.53) | GNAI3GNAO1GNAI1NOD1TLR2 | |
| SCHEMBL444218 | 0.87 | NOD1 (0.53) | GNAI3GNAO1GNAI1NOD1TLR2 | |
| SCHEMBL444219 | 0.87 | NOD1 (0.53) | GNAI3GNAO1GNAI1NOD1TLR2 | |
| SCHEMBL13079511 | 0.84 | GNAI3 (0.54) | GNAI3GNAO1GNAI1NOD1RRM1 | |
| SCHEMBL8520845 | 0.83 | NOD1 (0.54) | GNAI3GNAO1GNAI1NOD1RRM1 | |
| SCHEMBL8821920 | 0.82 | NOD1 (0.65) | NOD1TLR2KMT2ASIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338643-B2 | Reagent for introduction of protein or gene | WASEDA UNIVERSITY (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20100291672-A1 | REAGENT FOR INTRODUCTION OF PROTEIN OR GENE | WASEDA UNIVERSITY (JP) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100291672-A1 | REAGENT FOR INTRODUCTION OF PROTEIN OR GENE | C1S, SGMS1, CERT1 | GNAI3 3465/4885GNAO1 2905/4885GNAI1 1693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.