SCHEMBL906115

SCHEMBL906115

CCCCCCCCCCCCCCOC(=O)CC[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)OCCCCCCCCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 6/20 0.53
GNAI3 P08754 1/20 0.51
GNAO1 P09471 1/20 0.51
GNAI1 P63096 1/20 0.51
TLR2 O60603 3/20 0.49
DPP8 Q6V1X1 2/20 0.48
DPP9 Q86TI2 2/20 0.48
DPP7 Q9UHL4 2/20 0.48
HTR2C P28335 1/20 0.45
DPP4 P27487 1/20 0.43
KMT2A Q03164 1/20 0.42
SIRT6 Q8N6T7 1/20 0.42
SIRT1 Q96EB6 1/20 0.42
ERAP2 Q6P179 1/20 0.42
LNPEP Q9UIQ6 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL411636 1.00 NOD1 (0.53) NOD1GNAI3GNAO1GNAI1TLR2
SCHEMBL444217 1.00 NOD1 (0.53) NOD1GNAI3GNAO1GNAI1TLR2
SCHEMBL444219 1.00 NOD1 (0.53) NOD1GNAI3GNAO1GNAI1TLR2
SCHEMBL444218 1.00 NOD1 (0.53) NOD1GNAI3GNAO1GNAI1TLR2
SCHEMBL8520845 0.96 NOD1 (0.54) NOD1GNAI3GNAO1GNAI1TLR2
SCHEMBL13562003 0.94 SLC6A5 (0.49) NOD1GNAI3GNAO1GNAI1TLR2
Hydrochloric Acid SCHEMBL31420399 0.93 SLC6A5 (0.48) NOD1GNAI3GNAO1GNAI1TLR2
SCHEMBL27779757 0.92 NOD1 (0.61) NOD1GNAI3GNAO1GNAI1TLR2
SCHEMBL905947 0.89 GNAI3 (0.52) NOD1GNAI3GNAO1GNAI1TLR2
SCHEMBL13050781 0.89 GNAI3 (0.52) NOD1GNAI3GNAO1GNAI1TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080131455-A1 Antigen Delivery Compositions And Methods Of Use PDS BIOTECHNOLOGY CORPORATION (US) 2008-06-05 US claimed
US-7303881-B2 Antigen delivery compositions and methods of use PDS BIOTECHNOLOGY CORPORATION (US) 2007-12-04 US claimed
WO-2025235559-A1 IL-12 FUSION PROTEIN FORMULATIONS AND METHODS OF USE THEREOF PDS BIOTECHNOLOGY CORPORATION (US) 2025-11-13 WO disclosed
WO-2024086169-A2 NOVEL NON-HLA RESTRICTED T CELL VACCINE FOR TCR GAMMA ALTERNATE READING FRAME PROTEIN (TARP) PROTEIN EXPRESSING CANCERS PDS BIOTECHNOLOGY CORPORATION (US) 2024-04-25 WO disclosed
WO-2024086380-A2 RECOMBINANT PROTEIN VACCINES FORMULATED WITH ENANTIO-SPECIFIC CATIONIC LIPID R-DOTAP AND METHODS OF USE THEREOF PDS BIOTECHNOLOGY CORPORATION (US) 2024-04-25 WO disclosed
WO-2024086290-A2 NOVEL T CELL ACTIVATING IMMUNOTHERAPEUTIC FOR TREATMENT OF MUCIN 1 PROTEIN EXPRESSING HUMAN CANCERS PDS BIOTECHNOLOGY CORPORATION (US) 2024-04-25 WO disclosed
US-11911359-B2 Stimulation of an immune response by cationic lipids PDS BIOTECHNOLOGY CORPORATION (US) 2024-02-27 US disclosed
US-11904015-B2 Vaccine compositions and methods of use PDS BIOTECHNOLOGY CORPORATION (US) 2024-02-20 US disclosed
US-11801257-B2 Stimulation of an immune response by enantiomers of cationic lipids PDS BIOTECHNOLOGY CORPORATION (US) 2023-10-31 US disclosed
EP-4247493-A1 METHODS AND COMPOSITIONS COMPRISING CATIONIC LIPIDS FOR IMMUNOTHERAPY BY DIRECT TUMOR INJECTION PDS Biotechnology Corporation (US) 2023-09-27 EP disclosed
US-20230285551-A1 LIPIDS AS SYNTHETIC VECTORS TO ENHANCE ANTIGEN PROCESSING AND PRESENTATION EX-VIVO IN DENDRITIC CELL THERAPY PDS BIOTECHNOLOGY CORPORATION 2023-09-14 US disclosed
EP-2276495-A1 STIMULATION OF AN IMMUNE RESPONSE BY ENANTIOMERS OF CATIONIC LIPIDS PDS Biotechnology Corporation (US) 2011-01-26 EP disclosed
EP-2125011-A2 STIMULATION OF AN IMMUNE RESPONSE BY CATIONIC LIPIDS PDS Biotechnology Corporation (US) 2009-12-02 EP disclosed
WO-2009129227-A1 STIMULATION OF AN IMMUNE RESPONSE BY ENANTIOMERS OF CATIONIC LIPIDS PDS BIOTECHNOLOGY CORPORATION (US) 2009-10-22 WO disclosed
US-20090017057-A1 STIMULATION OF AN IMMUNE RESPONSE BY CATIONIC LIPIDS PDS BIOTECHNOLOGY CORPORATION (US) 2009-01-15 US disclosed
WO-2008116078-A9 STIMULATION OF AN IMMUNE RESPONSE BY CATIONIC LIPIDS PDS BIOTECHNOLOGY CORP (US) 2008-11-20 WO disclosed
WO-2008116078-A2 STIMULATION OF AN IMMUNE RESPONSE BY CATIONIC LIPIDS PDS BIOTECHNOLOGY CORPORATION (US) 2008-09-25 WO disclosed
US-20080131455-A1 Antigen Delivery Compositions And Methods Of Use PDS BIOTECHNOLOGY CORPORATION (US) 2008-06-05 US disclosed
US-7303881-B2 Antigen delivery compositions and methods of use PDS BIOTECHNOLOGY CORPORATION (US) 2007-12-04 US disclosed
US-20060008472-A1 Antigen delivery compositions and methods of use PDS BIOTECHNOLOGY CORPORATION 2006-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11801257-B2 Stimulation of an immune response by enantiomers of cationic lipids C3AR1, FFAR1, FFAR3 NOD1 449/4885GNAI3 1372/4885GNAO1 2951/4885
US-20080131455-A1 Antigen Delivery Compositions And Methods Of Use CD74, CD47, HAVCR2 NOD1 552/4885GNAI3 1705/4885GNAO1 4070/4885
US-20090017057-A1 STIMULATION OF AN IMMUNE RESPONSE BY CATIONIC LIPIDS CD69, CD14, MYD88 NOD1 408/4885GNAI3 598/4885GNAO1 3084/4885
US-11911359-B2 Stimulation of an immune response by cationic lipids CD69, CD14, MYD88 NOD1 408/4885GNAI3 598/4885GNAO1 3084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.