SCHEMBL130494

SCHEMBL130494

COC(=O)c1ccc2ccc(O)cc2c1C(=O)OC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.61
CA1 P00915 4/20 0.61
CA2 P00918 4/20 0.61
CA7 P43166 4/20 0.61
CA9 Q16790 4/20 0.61
CA14 Q9ULX7 4/20 0.61
PDK2 Q15119 1/20 0.61
PDK4 Q16654 1/20 0.61
GAA P10253 4/20 0.45
MAPT P10636 7/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 4/20 0.43
HPGD P15428 4/20 0.43
HSD17B10 Q99714 4/20 0.43
PKM P14618 3/20 0.43
CYP3A4 P08684 2/20 0.43
ALOX15 P16050 2/20 0.43
EGFR P00533 2/20 0.43
CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10585851 0.83 GAA (0.58) CA12CA1CA2CA7CA9
SCHEMBL10341612 0.81 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL2114008 0.81 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL29404644 0.81 NCEH1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL71131 0.81 NCEH1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL3679271 0.80 ALDH1A1 (0.51) CA12CA1CA2CA7CA9
SCHEMBL131009 0.80 NR4A2 (0.40) CA12CA1CA2CA7CA9
Methyl 2,4-Dihydroxybenzoate SCHEMBL28334880 0.78 CA12 (0.96) CA12CA1CA2CA7CA9
SCHEMBL158999 0.77 CA12 (0.74) CA12CA1CA2CA7CA9
SCHEMBL3678050 0.77 NCEH1 (0.51) MAPTMEN1KMT2AKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1521125-B1 Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound RICOH CO LTD (JP) 2012-03-07 EP disclosed
US-7309552-B2 Containing the reaction product of a dibenzo [a,c]phenadine-2,7-bisdiazonium salt and a coupler such as N-benzyl-2-hydroxy-7,8-naphthalic acid imide; stilbene charge transport material; 1alkylidene-2,3-diphenylindene acceptor; biphenol; copolycarbonate containing arylamine groups; highly durable RICOH COMPANY, LTD. (JP) 2007-12-18 US disclosed
US-7175958-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
US-20050266331-A1 Electrophotographic photoconductor, electrophotography, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound RICOH COMPANY, LTD. (JP) 2005-12-01 US disclosed
US-20050112487-A1 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same SHOSHI MASAYUKI (JP) 2005-05-26 US disclosed
EP-1521125-A1 Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound Ricoh Company (JP) 2005-04-06 EP disclosed
US-6849367-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and a process cartridge for the same RICOH COMPANY, LTD. (JP) 2005-02-01 US disclosed
US-20030190540-A1 Electrophotographic photoconductor, process for forming an image, image forming apparatus and a process cartridge for the same RICOH COMPANY, LTD. (JP) 2003-10-09 US disclosed