SCHEMBL131009

SCHEMBL131009

COC(=O)c1ccc2ccc(OC(C)(C)C)cc2c1C(=O)OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.40
KDM4E B2RXH2 4/20 0.40
MAPT P10636 3/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
ABL1 P00519 1/20 0.40
MTNR1A P48039 1/20 0.40
PLA2G2A P14555 4/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
PDK2 Q15119 1/20 0.38
PDK4 Q16654 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
L3MBTL1 Q9Y468 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130494 0.80 CA12 (0.61) KDM4EMAPTALDH1A1HPGDCA12
SCHEMBL5438827 0.77 KMT2A (0.49) KDM4EMAPTALDH1A1HPGDMEN1
SCHEMBL3679271 0.77 ALDH1A1 (0.51) KDM4EMAPTALDH1A1HPGDSLC6A2
SCHEMBL10585851 0.77 GAA (0.58) KDM4EMAPTALDH1A1HPGDABL1
SCHEMBL7971285 0.77 NR4A2 (0.50) NR4A2KDM4EMAPTALDH1A1HPGD
SCHEMBL28370520 0.75 KDM4E (0.44) NR4A2KDM4EMAPTALDH1A1HPGD
SCHEMBL20628874 0.75 CA12 (0.59) KDM4EMAPTALDH1A1HPGDCA12
SCHEMBL29404644 0.74 NCEH1 (0.59) NR4A2KDM4EMAPTALDH1A1HPGD
SCHEMBL71131 0.74 NCEH1 (0.59) NR4A2KDM4EMAPTALDH1A1HPGD
SCHEMBL3678050 0.71 NCEH1 (0.51) NR4A2KDM4EMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1521125-B1 Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound RICOH CO LTD (JP) 2012-03-07 EP disclosed
US-7309552-B2 Containing the reaction product of a dibenzo [a,c]phenadine-2,7-bisdiazonium salt and a coupler such as N-benzyl-2-hydroxy-7,8-naphthalic acid imide; stilbene charge transport material; 1alkylidene-2,3-diphenylindene acceptor; biphenol; copolycarbonate containing arylamine groups; highly durable RICOH COMPANY, LTD. (JP) 2007-12-18 US disclosed
US-7175958-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
US-20050266331-A1 Electrophotographic photoconductor, electrophotography, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound RICOH COMPANY, LTD. (JP) 2005-12-01 US disclosed
US-20050112487-A1 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same SHOSHI MASAYUKI (JP) 2005-05-26 US disclosed
EP-1521125-A1 Electrophotographic photoconductor, electrophotographic method, electrophotographic apparatus, process cartridge for electrophotographic apparatus and azo compound Ricoh Company (JP) 2005-04-06 EP disclosed
US-6849367-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and a process cartridge for the same RICOH COMPANY, LTD. (JP) 2005-02-01 US disclosed
US-20030190540-A1 Electrophotographic photoconductor, process for forming an image, image forming apparatus and a process cartridge for the same RICOH COMPANY, LTD. (JP) 2003-10-09 US disclosed