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SCHEMBL13049490

SCHEMBL13049490

Cc1cc(C)c(-c2cc(C)c(-c3ccc(N(c4ccc(-c5cc(C)c(-c6c(C)cc(C)cc6C)cc5C)c(C)c4)c4ccc(-c5cc(C)c(-c6c(C)cc(C)cc6C)cc5C)c(C)c4)cc3C)cc2C)c(C)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 1/20 0.31
▸ LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13049519 0.83 MAPT (0.37) LMNA
SCHEMBL14825137 0.82 MEN1 (0.32) —
SCHEMBL13049496 0.82 MAPT (0.41) LMNA
SCHEMBL13921982 0.81 CRHR1 (0.32) PDK2
SCHEMBL13049533 0.80 LMNA (0.39) LMNA
SCHEMBL9285148 0.80 ESR1 (0.31) LMNA
SCHEMBL18286378 0.80 MEN1 (0.31) —
SCHEMBL11966915 0.80 APP (0.36) PDK2LMNA
SCHEMBL1702280 0.78 ALDH1A1 (0.42) LMNA
SCHEMBL14825140 0.76 RARB (0.38) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7839075-B2 Organic electroluminescent element, illuminator and display KONICA MINOLTA HOLDINGS, INC. (JP) 2010-11-23 — — US disclosed
US-7839075-B2 Organic electroluminescent element, illuminator and display KONICA MINOLTA HOLDINGS, INC. (JP) 2010-11-23 — — US disclosed