Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13052018 | 0.85 | ALDH1A1 (0.55) | MAPTNPC1SMN1; SMN2RAB9ATAAR1 | |
| SCHEMBL5974975 | 0.83 | MAPT (0.54) | MAPTNPC1SMN1; SMN2RAB9ATAAR1 | |
| SCHEMBL29957192 | 0.83 | EPHX2 (0.58) | MAPTNPC1SMN1; SMN2RAB9ATAAR1 | |
| SCHEMBL12290183 | 0.81 | MAPT (0.60) | MAPTNPC1SMN1; SMN2ALDH1A1HDAC1 | |
| SCHEMBL20709030 | 0.81 | EPHX1 (0.77) | SMN1; SMN2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL27440837 | 0.81 | MAPT (0.57) | MAPTNPC1SMN1; SMN2RAB9ATAAR1 | |
| SCHEMBL27439714 | 0.81 | MAPT (0.57) | MAPTNPC1SMN1; SMN2RAB9ATAAR1 | |
| SCHEMBL17328296 | 0.80 | MAPT (0.59) | MAPTNPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29952991 | 0.79 | MAPT (0.60) | MAPTNPC1SMN1; SMN2RAB9ATAAR1 | |
| SCHEMBL5974338 | 0.79 | MAPT (0.56) | MAPTNPC1SMN1; SMN2RAB9ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786249-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-7772359-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-7632914-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2009-12-15 | — | — | US | disclosed |
| US-20090012606-A1 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS | PACETTI STEPHEN D | 2009-01-08 | — | — | US | disclosed |
| US-20090012243-A1 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS | PACETTI STEPHEN D | 2009-01-08 | — | — | US | disclosed |
| US-20090012259-A1 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS | PACETTI STEPHEN D | 2009-01-08 | — | — | US | disclosed |
| US-7435788-B2 | Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2008-10-14 | — | — | US | disclosed |