Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 13/20 | 0.79 |
| ▸ | PGR | P06401 | 4/20 | 0.75 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12893396 | 1.00 | NR3C1 (0.79) | NR3C1PGRARDHODHHTR1A | |
| SCHEMBL1261756 | 1.00 | NR3C1 (0.79) | NR3C1PGRARDHODHHTR1A | |
| SCHEMBL12919535 | 0.89 | NR3C1 (0.63) | NR3C1PGRAR | |
| SCHEMBL12893369 | 0.89 | NR3C1 (0.63) | NR3C1PGRAR | |
| SCHEMBL1262087 | 0.89 | NR3C1 (0.63) | NR3C1PGRAR | |
| SCHEMBL3749873 | 0.88 | NR3C1 (1.00) | NR3C1PGRARDHODHMEN1 | |
| SCHEMBL1261598 | 0.88 | NR3C1 (1.00) | NR3C1PGRARDHODHMEN1 | |
| SCHEMBL1261596 | 0.88 | NR3C1 (1.00) | NR3C1PGRARDHODHMEN1 | |
| SCHEMBL1261715 | 0.86 | NR3C1 (1.00) | NR3C1PGRARDHODHMEN1 | |
| SCHEMBL12893347 | 0.80 | NR3C1 (0.81) | NR3C1PGRARMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298311-A1 | TETRAHYDRONAPHTHALENE DERIVATES, PROCESS FOR PREPARING THEM AND THEIR USE AS ANTIINFLAMMATORY AGENTS | BERGER MARKUS | 2010-11-25 | — | — | US | disclosed |
| US-20100298311-A1 | TETRAHYDRONAPHTHALENE DERIVATES, PROCESS FOR PREPARING THEM AND THEIR USE AS ANTIINFLAMMATORY AGENTS | BERGER MARKUS | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298311-A1 | TETRAHYDRONAPHTHALENE DERIVATES, PROCESS FOR PREPARING THEM AND THEIR USE AS ANTIINFLAMMATORY AGENTS | TNF, IL1B, DHPS | NR3C1 286/4885PGR 2807/4885AR 2826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.