Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14073892 | 0.81 | HSD11B1 (0.56) | HSD11B1KMT2ACCR5LMNAHTT | |
| SCHEMBL11853584 | 0.81 | HSD11B1 (0.56) | HSD11B1TDP1KMT2ALMNAHTT | |
| SCHEMBL6425280 | 0.80 | HSD11B1 (0.69) | HSD11B1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL7924228 | 0.79 | HSD11B1 (0.67) | HSD11B1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL22077209 | 0.77 | HSD11B1 (0.51) | HSD11B1TDP1KMT2APSIP1CCR5 | |
| SCHEMBL27540835 | 0.77 | HSD11B1 (0.65) | HSD11B1TDP1KMT2ALMNAHTT | |
| SCHEMBL10511655 | 0.77 | HSD11B1 (0.65) | HSD11B1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL26680105 | 0.76 | HSD11B1 (1.00) | HSD11B1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL27339735 | 0.74 | HSD11B1 (0.51) | HSD11B1TDP1KMT2APSIP1CCR5 | |
| SCHEMBL30657620 | 0.74 | TAS2R14 (0.53) | HSD11B1LMNAHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318956-B2 | Spiroheterocyclic tetronic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2012-11-27 | — | — | US | disclosed |
| US-20100298145-A1 | Spiroheterocyclic Tetronic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298145-A1 | Spiroheterocyclic Tetronic Acid Derivatives | DDT, PTPRG, WIZ | HSD11B1 1276/4885TDP1 2005/4885KMT2A 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.