Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 5/20 | 0.31 |
| ▸ | ACHE | P22303 | 5/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782382 | 0.87 | L3MBTL1 (0.34) | KMT2AL3MBTL1 | |
| SCHEMBL12362067 | 0.83 | BCHE (0.32) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL782275 | 0.83 | L3MBTL1 (0.32) | L3MBTL1 | |
| SCHEMBL12231732 | 0.81 | BCHE (0.30) | BCHEACHE | |
| SCHEMBL732799 | 0.81 | SLC6A3 (0.31) | THRB | |
| SCHEMBL782197 | 0.80 | TSHR (0.37) | KDM4EMEN1POLBGAAKMT2A | |
| SCHEMBL12214982 | 0.80 | POLB (0.31) | KDM4EPOLB | |
| SCHEMBL14464274 | 0.80 | POLB (0.31) | KDM4EPOLB | |
| SCHEMBL13039867 | 0.80 | BCHE (0.30) | BCHEACHE | |
| SCHEMBL782574 | 0.80 | HDAC3 (0.31) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432785-B1 | HERBICIDAL SPIROHETEROCYCLIC TETRONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-10-15 | — | — | EP | disclosed |
| US-20130012384-A1 | Spiroheterocyclic Tetronic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2013-01-10 | — | — | US | disclosed |
| US-20130012384-A1 | Spiroheterocyclic Tetronic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2013-01-10 | — | — | US | disclosed |
| US-8318956-B2 | Spiroheterocyclic tetronic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2012-11-27 | — | — | US | disclosed |
| US-8318956-B2 | Spiroheterocyclic tetronic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2012-11-27 | — | — | US | disclosed |
| WO-2010133337-A1 | HERBICIDAL SPIROHETEROCYCLIC TETRONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | WO | disclosed |
| US-20100298145-A1 | Spiroheterocyclic Tetronic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | US | disclosed |
| US-20100298145-A1 | Spiroheterocyclic Tetronic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298145-A1 | Spiroheterocyclic Tetronic Acid Derivatives | DDT, PTPRG, WIZ | KDM4E 4133/4885MEN1 4277/4885POLB 2155/4885 |
| US-20130012384-A1 | Spiroheterocyclic Tetronic Acid Derivatives | DDT, PTPRG, WIZ | KDM4E 4133/4885MEN1 4277/4885POLB 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.