Narcissin

Narcissin

SCHEMBL1305418

COc1cc(-c2oc3cc(O)cc(O)c3c(=O)c2O[C@@H]2O[C@H](CO[C@H]3O[C@H](C)[C@@H](O)[C@H](O)[C@@H]3O)[C@@H](O)[C@H](O)[C@H]2O)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ P4HB P07237 3/20 1.00
▸ SYNJ2 O15056 1/20 1.00
▸ KDM4E B2RXH2 5/20 0.85
▸ MAPT P10636 3/20 0.85
▸ HES1 Q14469 2/20 0.85
▸ FANCF Q9NPI8 2/20 0.85
▸ POLB P06746 2/20 0.85
▸ GAA P10253 2/20 0.85
▸ XDH P47989 2/20 0.85
▸ EPHX2 P34913 2/20 0.85
▸ KDM1A O60341 1/20 0.85
▸ PRSS1 P07477 1/20 0.85
▸ PRSS2 P07478 1/20 0.85
▸ ADRA2A P08913 1/20 0.85
▸ HMGB1 P09429 1/20 0.85
▸ CFTR P13569 1/20 0.85
▸ ADRA2C P18825 1/20 0.85
▸ MAOA P21397 1/20 0.85
▸ ACHE P22303 1/20 0.85
▸ MAPK1 P28482 1/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Narcissin SCHEMBL31236364 1.00 P4HB (1.00) P4HBSYNJ2KDM4EMAPTHES1
Narcissin SCHEMBL1305421 1.00 P4HB (1.00) P4HBSYNJ2KDM4EMAPTHES1
Narcissin SCHEMBL30389758 1.00 P4HB (1.00) P4HBSYNJ2KDM4EMAPTHES1
Narcissin SCHEMBL7167500 1.00 P4HB (1.00) P4HBSYNJ2KDM4EMAPTHES1
Narcissin SCHEMBL15773535 1.00 P4HB (1.00) P4HBSYNJ2KDM4EMAPTHES1
Narcissin SCHEMBL29516911 1.00 P4HB (1.00) P4HBSYNJ2KDM4EMAPTHES1
Narcissin SCHEMBL31236367 1.00 P4HB (1.00) P4HBSYNJ2KDM4EMAPTHES1
Rutin SCHEMBL6427268 0.95 P4HB (0.90) P4HBSYNJ2KDM4EMAPTHES1
SCHEMBL30305712 0.95 P4HB (0.90) P4HBSYNJ2KDM4EMAPTHES1
SCHEMBL25292788 0.94 P4HB (0.89) P4HBSYNJ2KDM4EMAPTHES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4655410-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE Symrise AG (DE) 2025-12-03 — — EP claimed
EP-4650770-A1 METHOD FOR CONSTRUCTING CHICORY-PORIA COMPOUND FINGERPRINT, AND FINGERPRINT AND USE THEREOF Beijing University of Chinese Medicine (CN) 2025-11-19 — — EP claimed
EP-4558157-A1 ANHYDROUS EXTRACT OF STEMLESS LEAVES OF HIPPOPHAE RHAMNOIDES OR COMPOSITION COMPRISING SAID EXTRACT FOR USE IN MAINTAINING AND/OR IMPROVING SKIN MICROCIRCULATION GATTEFOSSE SAS (FR) 2025-05-28 — — EP claimed
WO-2025035717-A1 METHOD FOR CONSTRUCTING CHICORY-PORIA COMPOUND FINGERPRINT, AND FINGERPRINT AND USE THEREOF 北京中医药大学 2025-02-20 — — WO claimed
WO-2024156879-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE SYMRISE AG (DE) 2024-08-02 — — WO claimed
WO-2024156359-A1 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE SYMRISE AG (DE) 2024-08-02 — — WO claimed
WO-2024018160-A1 ANHYDROUS EXTRACT OF STEMLESS LEAVES OF HIPPOPHAE RHAMNOIDES OR COMPOSITION COMPRISING SAID EXTRACT FOR USE IN MAINTAINING AND/OR IMPROVING SKIN MICROCIRCULATION GATTEFOSSE SAS (FR) 2024-01-25 — — WO claimed
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 — — WO claimed
WO-2023284777-A1 COPOLYMER FILM, ENZYME CATALYSIS SELF-ASSEMBLY SYNTHESIS METHOD THEREFOR, AND APPLICATION THEREOF 中国科学院天津工业生物技术研究所 2023-01-19 — — WO claimed
CN-115612699-A Copolymer membrane and enzymatic self-assembly synthesis method and application thereof at gas-liquid interface 中国科学院天津工业生物技术研究所 2023-01-17 — — CN claimed
US-20030104082-A1 Antimicrobial prevention and treatment of human immunedeficience virus and other infectious diseases MCGINLEY PARTNERS, LLC (US) 2003-06-05 — — US claimed
JP-2003504327-A — — 2003-02-04 — — JP claimed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 — — EP claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 — — WO claimed
CN-1258191-A Antimicrobial prevention and treatment of human immunodeficiency virus and other infectious diseases MERYL SQUIRES (US) 2000-06-28 — — CN claimed
US-6063383-A Pharmaceutical suppository composites for fever and influenza and method of producing the composites HSU WU-CHING (TW) 2000-05-16 — — US claimed
EP-0980203-A1 ANTIMICROBIAL PREVENTION AND TREATMENT OF HUMAN IMMUNEDEFICIENCY VIRUS AND OTHER INFECTIOUS DISEASES Squires, Meryl (US) 2000-02-23 — — EP claimed
US-6004560-A OBTAINING A LIQUID BY BOILING BUPLEURUM SCORZONERIFOLIUM WILLD, RADIX LASTIDIS INDIGOTICA AND FOLIUM LASTIDIS FOR A LONG TIME IN WATER, AND THEN MIXING THE LIQUID THUS OBTAINED WITH VITAMIN C HSU WU-CHING (TW) 1999-12-21 — — US claimed
WO-1998042188-A1 ANTIMICROBIAL PREVENTION AND TREATMENT OF HUMAN IMMUNEDEFICIENCY VIRUS AND OTHER INFECTIOUS DISEASES SQUIRES MERYL (US) 1998-10-01 — — WO claimed
US-4617293-A Flavonoid phosphate salts of aminoglycoside antibiotics MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1986-10-14 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030104082-A1 Antimicrobial prevention and treatment of human immunedeficience virus and other infectious diseases CD14, CD59, SLC19A1 P4HB 3521/4885SYNJ2 4493/4885KDM4E 3962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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