SCHEMBL1305477

SCHEMBL1305477

N#COc1ccccc1-c1ccccc1OC#N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
ALDH1A1 P00352 4/20 0.33
HTR7 P34969 2/20 0.32
APP P05067 1/20 0.32
TSHR P16473 2/20 0.32
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
PGR P06401 2/20 0.31
AR P10275 2/20 0.31
NPSR1 Q6W5P4 1/20 0.31
KDM4E B2RXH2 2/20 0.30
HPGD P15428 2/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2159608 0.86 MAPK1 (0.44) ALDH1A1HTR7ARKDM4EHPGD
SCHEMBL30159634 0.86 CA1 (0.38) CA12CA1CA2CA4CA7
SCHEMBL159732 0.86 CA1 (0.38) CA12CA1CA2CA4CA7
SCHEMBL28316502 0.85 HTR7 (0.33) ALDH1A1HTR7HPGD
Hydrogen Sulfide SCHEMBL27519355 0.84 MAPK1 (0.43) ALDH1A1HTR7ARKDM4EHPGD
SCHEMBL3424396 0.82 NCOA1 (0.39) CA1CA2CA9ALDH1A1POLB
SCHEMBL17847444 0.82 L3MBTL1 (0.40) ALDH1A1HTR7TSHRGAAAR
Ethylene SCHEMBL27752633 0.81 CA12 (0.35) CA12CA1CA2CA4CA7
SCHEMBL31166665 0.81 NCOA1 (0.41) POLBGAAPGRARESR2
SCHEMBL1324603 0.79 AR (0.38) CA12CA1CA2CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288458-A1 Reworkable thermosetting resin composition KLEMARCZYK PHILIP T 2005-12-29 US claimed
EP-1268457-A4 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORP (US) 2005-07-20 EP claimed
US-6887737-B1 Epoxidized acetals and thioacetals, episulfidized acetals and thioacetals, and reworkable thermosetting resin compositions formulated therefrom HENKEL CORPORATION (US) 2005-05-03 US claimed
US-6770691-B2 (A) BROMINE-FREE EPOXY RESIN AND CURING AGENT; (B) A FLAME RETARDANT ADDITIVE THAT IS THE CONDENSATION PRODUCT OF A BROMINATED PHENOL AND A CYANURIC HALIDE; (C) THERMOPLASTIC RESIN (POLYPHENYLENE ETHER), AND (D) A CYANATE ESTER GENERAL ELECTRIC COMPANY 2004-08-03 US claimed
US-6657031-B1 Curable; polyepoxide reworkable through thermal decomposition; printed circuits, semiconductors LOCTITE CORPORATION 2003-12-02 US claimed
JP-2003529643-A 2003-10-07 JP claimed
WO-2003051955-A1 EPOXIDIZED ACETALS AND THIOACETALS, EPISULFIDIZED ACETALS AND THIOACETALS, AND REWORKABLE THERMOSETTING RESIN COMPOSITIONS FORMULATED THEREFROM HENKEL CORPORATION (US) 2003-06-26 WO claimed
US-6572980-B1 Curable epoxy or episulfide containing aromatic compound and curing agent; repair, replacement, recovery and/or recycling of electronics HENKEL LOCTITE CORPORATION 2003-06-03 US claimed
EP-1268457-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2003-01-02 EP claimed
JP-2002540235-A 2002-11-26 JP claimed
US-20020107308-A1 Curable epoxy resin compositions and the cured residues thereof CITIBANK, N.A., AS COLLATERAL AGENT 2002-08-08 US claimed
WO-2001074798-A1 REWORKABLE COMPOSITION OF OXIRANE(S) OR THIIRANE(S)-CONTAINING RESIN AND CURING AGENT LOCTITE CORPORATION (US) 2001-10-11 WO claimed
EP-1090057-A1 REWORKABLE THERMOSETTING RESIN COMPOSITIONS LOCTITE CORPORATION (US) 2001-04-11 EP claimed
WO-2000056799-A1 REWORKABLE THERMOSETTING RESIN COMPOSITIONS LOCTITE CORPORATION (US) 2000-09-28 WO claimed
EP-0295375-A2 Process for the preparation of cyanate resin-based prepregs and films which maintain their tack BASF Aktiengesellschaft (DE) 1988-12-21 EP claimed
US-20260117059-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, CURED PRODUCT, PREPREG, LAMINATE, AND SEMICONDUCTOR SUBSTRATE NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2026-04-30 US disclosed
US-20260109853-A1 CURABLE RESIN COMPOSITION AND CURED PRODUCT OF SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2026-04-23 US disclosed
US-4116946-A OLEFIN, CATALYST BAYER AKTIENGESELLSCHAFT (DE) 1978-09-26 US disclosed
US-4094852-A Process for the production of polytriazines in the presence of high-boiling esters BAYER AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed
US-4066577-A HIGH MOLECULAR WEIGHT POLYTRIAZINES OF SOLUBLE POLYMERIC N-CYANO-ISOUREA ETHERS BAYER AKTIENGESELLSCHAFT (DT) 1978-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260117059-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, CURED PRODUCT, PREPREG, LAMINATE, AND SEMICONDUCTOR SUBSTRATE RAD51, ASH2L, H1-0 PIM1 3737/4885CA12 4235/4885CA1 1913/4885
US-20260109853-A1 CURABLE RESIN COMPOSITION AND CURED PRODUCT OF SAME PSMA1, PSMB10, RAD51 PIM1 1571/4885CA12 2520/4885CA1 1012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.