SCHEMBL1305677

SCHEMBL1305677

Cc1cc(C)cc([P](=O)c2cc(C)cc(C)c2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
TSHR P16473 3/20 0.42
TPMT P51580 1/20 0.39
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ACHE P22303 3/20 0.35
HSP90AA1 P07900 1/20 0.35
CCR6 P51684 1/20 0.35
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
C1S P09871 1/20 0.32
PRSS3 P35030 1/20 0.32
SELL P14151 1/20 0.32
SELP P16109 1/20 0.32
SELE P16581 1/20 0.32
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28231579 0.79 ALDH1A1 (0.47) ALDH1A1TSHRTPMTCYP3A4MAPK1
SCHEMBL8373256 0.76 ALDH1A1 (0.44) ALDH1A1TSHRTPMTCYP3A4MAPK1
SCHEMBL28425258 0.73 ALDH1A1 (0.57) ALDH1A1TSHRTPMTCYP3A4MAPK1
SCHEMBL19376983 0.73 ALDH1A1 (0.57) ALDH1A1TSHRTPMTCYP3A4MAPK1
SCHEMBL341533 0.73 ALDH1A1 (0.67) ALDH1A1TSHRTPMTCYP3A4MAPK1
SCHEMBL26115 0.73
SCHEMBL503226 0.72 ALDH1A1 (0.47) ALDH1A1TSHRTPMTCYP3A4MAPK1
SCHEMBL1304361 0.71 ACHE (0.55) ALDH1A1TSHRCYP3A4MAPK1TDP1
SCHEMBL183976 0.71 ACHE (0.50) ALDH1A1TDP1ACHECA1CA9
Formaldehyde SCHEMBL2965235 0.70 ALDH1A1 (0.53) ALDH1A1TSHRTPMTCYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119075972-A MoO reinforced by radio frequency plasma technology3/g-C3N4Catalyst and application of catalyst in phosphonation reaction 中国人民解放军军事科学院防化研究院 2024-12-06 CN claimed
CN-118908996-A A composition containing C (sp2) P bond or C (sp)3) Process for preparing organic phosphine compound of-P bond 烟台大学 2024-11-08 CN claimed
CN-115403623-B Method for preparing 2-pyrrolyl substituted phosphine oxide compound 湖南理工学院 2024-10-29 CN claimed
CN-118515707-A Ligand H4Hpda metal-organic framework material, preparation method and application thereof 浙江理工大学 2024-08-20 CN claimed
CN-114031639-B Preparation method of biphospide with P-O-C-P structure 烟台大学 2024-07-12 CN claimed
CN-114805430-B Preparation method of selenophosphide and thiophosphoride 烟台大学 2024-02-13 CN claimed
CN-111606945-B Preparation method of compound containing P-O bond or P-S bond 烟台大学 2023-06-20 CN claimed
CN-115403623-A Method for preparing 2-pyrrolyl substituted phosphine oxide compound 湖南理工学院 2022-11-29 CN claimed
CN-113773632-A Composition containing curable polyphenylene ether resin and application thereof 洛阳理工学院 2021-12-10 CN claimed
CN-119431439-A Method for preparing 2-formylaryl (phosphinic) phosphine/phosphoramide compound 岳阳凯茂化工材料有限公司 2025-02-14 CN disclosed
CN-119075972-A MoO reinforced by radio frequency plasma technology3/g-C3N4Catalyst and application of catalyst in phosphonation reaction 中国人民解放军军事科学院防化研究院 2024-12-06 CN disclosed
CN-118908996-A A composition containing C (sp2) P bond or C (sp)3) Process for preparing organic phosphine compound of-P bond 烟台大学 2024-11-08 CN disclosed
CN-115403623-B Method for preparing 2-pyrrolyl substituted phosphine oxide compound 湖南理工学院 2024-10-29 CN disclosed
CN-118515707-A Ligand H4Hpda metal-organic framework material, preparation method and application thereof 浙江理工大学 2024-08-20 CN disclosed
EP-1318156-A1 Novel asymmetric phosphine ligand Takasago International Corporation (JP) 2003-06-11 EP disclosed
EP-0755937-B1 Phosphine-phosphinite compound and process for preparing 4-[(R)-1'-formylethyl]-azetidin-2-one derivatives using the same TAKASAGO PERFUMERY CO LTD (JP) 2002-10-23 EP disclosed
US-6333291-B1 USEFUL AS A LIGAND OF CATALYSTS FOR ASYMMETRIC SYNTHESIS REACTIONS SUCH AS ASYMMETRIC HYDROGENATION REACTION TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-12-25 US disclosed
EP-1095946-A1 Optically active diphosphine compound, production intermediates therefor, transition metal complex containing the compound as ligand and asymmetric hydrogenation catalyst containing the complex Takasago International Corporation (JP) 2001-05-02 EP disclosed
US-5824822-A CATALYSTS FOR HYDROFORMYLATION OF COMPPOUNDS TO FORM INTERMEDIATES FOR CARBAPENEM ANTIBIOTICS TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-10-20 US disclosed
EP-0755937-A1 Phosphine-phosphinite compound and process for preparing 4-[(R)-1'-formylethyl]-azetidin-2-one derivatives using the same Takasago International Corporation (JP) 1997-01-29 EP disclosed