SCHEMBL183976

SCHEMBL183976

Cc1ccc([P](=O)c2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.50
TDP1 Q9NUW8 3/20 0.50
ALDH1A1 P00352 5/20 0.40
PKM P14618 2/20 0.40
HTT P42858 2/20 0.40
ATM Q13315 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
LMNA P02545 2/20 0.40
HPGD P15428 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NLRP1 Q9C000 1/20 0.40
MEN1 O00255 1/20 0.40
NTSR1 P30989 1/20 0.40
KMT2A Q03164 1/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
CYP2A6 P11509 1/20 0.39
GAA P10253 1/20 0.39
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2153490 0.89 ACHE (0.48) ACHETDP1ALDH1A1HTTLMNA
SCHEMBL28518753 0.87 ACHE (0.62) ACHETDP1ALDH1A1LMNASMN1; SMN2
SCHEMBL28443581 0.87 CES2 (0.50) ACHETDP1ALDH1A1HTTLMNA
SCHEMBL28528072 0.82 CYP1A1 (0.44) ACHEALDH1A1MEN1KMT2ACES2
SCHEMBL14540892 0.81 ACHE (0.50) ACHETDP1ALDH1A1PKMHTT
SCHEMBL28581741 0.75 ACHE (0.50) ACHETDP1ALDH1A1PKMHTT
SCHEMBL15661400 0.73 ACHE (0.57) ACHETDP1ALDH1A1PKMHTT
SCHEMBL34181 0.73 ACHE (0.57) ACHETDP1ALDH1A1PKMHTT
SCHEMBL7558573 0.71 ACHE (0.53) ACHETDP1ALDH1A1PKMHTT
SCHEMBL1305677 0.71 ALDH1A1 (0.42) ACHETDP1ALDH1A1CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119075972-A MoO reinforced by radio frequency plasma technology3/g-C3N4Catalyst and application of catalyst in phosphonation reaction 中国人民解放军军事科学院防化研究院 2024-12-06 CN claimed
CN-118908996-A A composition containing C (sp2) P bond or C (sp)3) Process for preparing organic phosphine compound of-P bond 烟台大学 2024-11-08 CN claimed
CN-115403623-B Method for preparing 2-pyrrolyl substituted phosphine oxide compound 湖南理工学院 2024-10-29 CN claimed
CN-114031639-B Preparation method of biphospide with P-O-C-P structure 烟台大学 2024-07-12 CN claimed
CN-114805430-B Preparation method of selenophosphide and thiophosphoride 烟台大学 2024-02-13 CN claimed
CN-113583042-B Preparation method of phosphoryl fluoride compound 烟台大学 2023-08-29 CN claimed
CN-116396328-A Diaryl phosphono-4-fluoro-1, 3-butadiene phosphate compound and preparation method thereof 南京工业大学 2023-07-07 CN claimed
CN-116284126-A Diaryl phosphono-4-fluoro-3-butene-1-one compound and preparation method thereof 南京工业大学 2023-06-23 CN claimed
CN-111606945-B Preparation method of compound containing P-O bond or P-S bond 烟台大学 2023-06-20 CN claimed
CN-115403623-A Method for preparing 2-pyrrolyl substituted phosphine oxide compound 湖南理工学院 2022-11-29 CN claimed
WO-2002068497-A1 METAL-CONTAINING COMPOSITION AND PROCESS THEREWITH E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-09-06 WO claimed
EP-1177042-A1 TITANIUM-CONTAINING CATALYST COMPOSITION AND PROCESSES THEREFOR AND THEREWITH E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-02-06 EP claimed
EP-0665237-B1 Process for the preparation of phosphorus containing dicarboxylic acid esters and dicarboxylic acids CLARIANT GMBH (DE) 2001-05-30 EP claimed
WO-2000062927-A1 TITANIUM-CONTAINING CATALYST COMPOSITION AND PROCESSES THEREFOR AND THEREWITH E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-10-26 WO claimed
US-6080834-A ORGANOTITANIUM COMPOUND, A HYDROXYCARBOXYLIC ACID OR AMINOCARBOXYLIC ACID COMPLEXING AGENT, SOLVENT, AND A PHOSPHONIC, A PHOSPHINIC, OR A PHOSPHINE PHOSPHORUS SOURCE; USE AS (TRANS)ESTERIFICATION, OR POLYMERIZATION CATALYST E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-06-27 US claimed
EP-0708109-B1 Process for the preparation of dicarbonic acids containing phosphorus CLARIANT GMBH (DE) 2000-03-01 EP claimed
US-5847184-A Process for preparing phosphorus-containing dicarboxylic acids HOECHST AKTIENGESELLSCHAFT (DE) 1998-12-08 US claimed
US-5693842-A Process for preparing phosphorus-containing dicarboxylic acids alkyl esters thereof HOECHST AG (DE) 1997-12-02 US claimed
EP-0337637-B1 2-(Heterocyclylthio)carbapenem derivatives their preparation and their use as antibiotics SANKYO CO (JP) 1994-11-30 EP claimed
EP-0597821-A1 2-(Heterocyclylthio)carbapenem derivatives their preparation and their use as antibiotics Sankyo Company Limited (JP) 1994-05-18 EP claimed