⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896428 | 0.83 | LMNA (0.35) | — | |
| SCHEMBL10063479 | 0.79 | ACLY (0.38) | — | |
| SCHEMBL19835942 | 0.79 | ACLY (0.38) | — | |
| SCHEMBL1881985 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL27974482 | 0.77 | TSHR (0.31) | — | |
| SCHEMBL17573453 | 0.76 | MEN1 (0.31) | — | |
| SCHEMBL4638990 | 0.75 | — | — | |
| SCHEMBL24484193 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL8273528 | 0.70 | GRM4 (0.32) | — | |
| SCHEMBL21547583 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7846972-B2 | Multimeric oleamide derivative having connexin-26 inhibiting potency and use thereof in cancer therapy, etc | The New Industrial Research Organization (JP) | 2010-12-07 | — | — | US | disclosed |
| US-20080089924-A1 | Multimeric Oleamide Derivative Having Connexin-26 Inhibiting Potency and Use Thereof in Cancer Therapy, etc. | THE RITSUMEIKAN TRUST (JP) | 2008-04-17 | — | — | US | disclosed |