Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 10/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005455 | 0.89 | HPGDS (0.45) | UTS2RATMHPGDHPGDSALDH1A1 | |
| SCHEMBL13060676 | 0.88 | BCL2 (0.45) | BCL2PTGS2UTS2RKIFC1HPGDS | |
| SCHEMBL13060831 | 0.88 | BCL2 (0.45) | BCL2PTGS2UTS2RKIFC1HPGDS | |
| SCHEMBL13061119 | 0.86 | HDAC4 (0.45) | BCL2PTGS2UTS2RKIFC1 | |
| SCHEMBL13060853 | 0.86 | HDAC4 (0.45) | BCL2PTGS2UTS2RKIFC1 | |
| SCHEMBL13060697 | 0.83 | MME (0.52) | BCL2UTS2RKIFC1HPGDSALDH1A1 | |
| SCHEMBL13060860 | 0.82 | BCL2 (0.42) | BCL2PTGS2UTS2RKIFC1HPGDS | |
| SCHEMBL13060829 | 0.82 | UTS2R (0.48) | BCL2UTS2RHPGDHPGDS | |
| SCHEMBL13061081 | 0.80 | SMYD3 (0.44) | BCL2UTS2RKIFC1ALDH1A1CHRM3 | |
| SCHEMBL13060678 | 0.79 | UTS2R (0.50) | UTS2RKIFC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |