Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13060802 | 0.89 | BCL2 (0.47) | HPGDSUTS2RALDH1A1ATMHPGD | |
| SCHEMBL13005424 | 0.88 | HPGDS (0.43) | HPGDSUTS2RF2F10PRSS1 | |
| SCHEMBL13005431 | 0.88 | HPGDS (0.43) | HPGDSUTS2RF2F10PRSS1 | |
| SCHEMBL13005434 | 0.87 | HDAC4 (0.45) | HPGDSUTS2RF2F10PRSS1 | |
| SCHEMBL13005436 | 0.87 | HDAC4 (0.45) | HPGDSUTS2RF2F10PRSS1 | |
| SCHEMBL13005665 | 0.86 | MME (0.51) | HPGDSUTS2RALDH1A1CTSBCTSL | |
| SCHEMBL13005497 | 0.84 | F2 (0.41) | HPGDSUTS2RF2F10PRSS1 | |
| SCHEMBL13005579 | 0.83 | KMT2A (0.47) | HPGDSUTS2RF2F10PRSS1 | |
| SCHEMBL13005542 | 0.82 | CTSD (0.40) | HPGDSUTS2RF2F10PRSS1 | |
| SCHEMBL13005545 | 0.81 | UTS2R (0.50) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |