Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 14/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13005704 | 0.86 | GHSR (0.49) | GHSRPOLB | |
| SCHEMBL11419707 | 0.85 | GHSR (0.53) | GHSRPOLBCHRNB2CHRNA4LTA4H | |
| SCHEMBL22288105 | 0.82 | POLB (0.50) | GHSRPOLBCHRNB2CHRNA4LTA4H | |
| SCHEMBL28458976 | 0.79 | POLB (0.56) | GHSRPOLBLTA4H | |
| SCHEMBL10132500 | 0.78 | POLB (0.58) | POLBLTA4H | |
| SCHEMBL13220245 | 0.76 | GHSR (0.53) | GHSRPOLBCHRNB2CHRNA4LTA4H | |
| SCHEMBL337613 | 0.74 | GHSR (0.67) | GHSRPOLB | |
| SCHEMBL337804 | 0.74 | GHSR (0.67) | GHSRPOLB | |
| SCHEMBL21216250 | 0.74 | POLB (0.54) | GHSRPOLBLTA4H | |
| SCHEMBL1355696 | 0.74 | OPRM1 (0.59) | GHSRPOLBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |