Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 18/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13061032 | 0.86 | GHSR (0.48) | GHSRPOLB | |
| SCHEMBL11419707 | 0.79 | GHSR (0.53) | GHSRPOLB | |
| SCHEMBL22288105 | 0.77 | POLB (0.50) | GHSRPOLB | |
| SCHEMBL22455707 | 0.75 | POLB (0.59) | GHSRPOLB | |
| SCHEMBL13220245 | 0.74 | GHSR (0.53) | GHSRPOLB | |
| SCHEMBL13005567 | 0.74 | SIGMAR1 (0.40) | — | |
| SCHEMBL13005578 | 0.74 | SIGMAR1 (0.40) | — | |
| SCHEMBL28458976 | 0.73 | POLB (0.56) | GHSRPOLB | |
| SCHEMBL21216250 | 0.71 | POLB (0.54) | GHSRPOLB | |
| SCHEMBL1355696 | 0.71 | OPRM1 (0.59) | GHSRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851637-B2 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners | INFINITY PHARMACEUTICALS, INC. (US) | 2010-12-14 | — | — | US | disclosed |